WordNet sense 1 (an unhappy and worried mental state):

perturbation, upset, upset

WordNet sense 2 ((psychiatry) a psychological disorder of thought or emotion; a more neutral term than mental illness):

folie, mental disorder, mental disturbance, psychological disorder

WordNet sense 3 (a disorderly outburst or tumult):

commotion, disruption, flutter, to-do, hoo-ha, hoo-hah, kerfuffle

WordNet sense 4 (electrical or acoustic activity that can disturb communication):

interference, noise

WordNet sense 5 (a noisy fight):

affray, fray, ruffle