WordNet sense 1 (eliminate completely and without a trace):

sweep away

WordNet sense 2 (use up (resources or materials)):

consume, deplete, eat, exhaust, eat up, run through, use up

WordNet sense 3 (remove from memory or existence):

erase

WordNet sense 4 (mark for deletion, rub off, or erase):

kill, obliterate

WordNet sense 5 (wipe out the effect of something):

cancel out

WordNet sense 6 (kill in large numbers):

annihilate, decimate, eliminate, eradicate, extinguish, carry off