WordNet sense 1 (the central meaning or theme of a speech or literary work):

burden, core, effect, gist

WordNet sense 2 (the choicest or most essential or most vital part of some idea or experience):

center, heart, kernel, marrow, meat, nitty-gritty, nub, pith, substance, sum, inwardness, heart and soul

WordNet sense 3 (a toiletry that emits and diffuses a fragrant odor):

perfume