WordNet sense 1 (the point located farthest from the middle of something):

extremum, extreme point

WordNet sense 2 (not within reasonable limits):

immoderate

WordNet sense 3 (of the greatest possible degree or extent or intensity):

utmost, uttermost

WordNet sense 4 (in an extreme degree):

intense

WordNet sense 5 (separated in space or coming from or going to a distance):

distant