WordNet sense 1 (affected with or marked by frenzy or mania uncontrolled by reason):

manic

WordNet sense 2 (marked by extreme lack of restraint or control):

wild

WordNet sense 3 (excessively agitated; transported with rage or other violent emotion):

frantic, frenetic, phrenetic

WordNet sense 4 (troubled emotionally and usually deeply):

agitated