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Synonyms for Lost (same or very similar meaning)

WordNet sense 1 (deeply absorbed in thought):
bemused, preoccupied

WordNet sense 2 (exhibiting or characterized by careful thought):
thoughtful

WordNet sense 3 (no longer known; irretrievable):
forgotten

WordNet sense 4 (incapable of being recovered or regained):
irrecoverable, unrecoverable

WordNet sense 5 (perplexed by many conflicting situations or statements; filled with bewilderment):
baffled, befuddled, bewildered, confounded, confused, mixed-up, mazed, at sea

WordNet sense 6 (full or difficulty or confusion or bewilderment):
perplexed

WordNet sense 7 (having lost your bearings; confused as to time or place or personal identity):
disoriented

WordNet sense 8 (not having position or goal definitely set or ascertained):
unoriented

WordNet sense 9 (surrendered as a penalty):
forfeit

WordNet sense 10 (destroyed physically or morally):
ruined

WordNet sense 11 (in danger of the eternal punishment of hell):
doomed, unredeemed

WordNet sense 12 (not used to good advantage):
wasted, squandered

WordNet sense 13 (not able to be found):
missing

WordNet sense 14 (no longer retained):
gone

WordNet sense 15 (unable to function; without help):
helpless

WordNet sense 16 (not caught with the senses or the mind):
missed

WordNet sense 17 (difficult to understand):
incomprehensible, uncomprehensible


From the ODE community, based on WordNetadd/edit