WordNet sense 1 (detrimental to physical or moral well-being):

unwholesome

WordNet sense 2 (suggesting the horror of death and decay):

ghoulish

WordNet sense 3 (unpleasant or disgusting especially to the senses):

offensive

WordNet sense 4 (caused by or altered by or manifesting disease or pathology):

diseased, pathological, pathologic

WordNet sense 5 (not in or exhibiting good health in body or mind):

unhealthy