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Antonyms for Natural (opposite meaning)

WordNet sense 1 (lowered in pitch by one chromatic semitone):
flat

WordNet sense 2 (raised in pitch by one chromatic semitone):
sharp

WordNet sense 3 (not existing in nature or subject to explanation according to natural laws; not physical or material):
supernatural

WordNet sense 4 (contrived by art rather than nature):
artificial

WordNet sense 5 (not in accordance with or determined by nature; contrary to nature):
unnatural


From the ODE community, based on WordNetadd/edit