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Synonyms for Screwball (same or very similar meaning)

WordNet sense 1 (a whimsically eccentric person):
crackpot, crank, fruitcake, nut, nutcase

WordNet sense 2 (foolish; totally unsound):
crazy, half-baked, softheaded

WordNet sense 3 (not practical; not workable or not given to practical matters):
impractical


From the ODE community, based on WordNetadd/edit