WordNet sense 1 (ratio of the opposite side to the hypotenuse of a right-angled triangle):

sine, sin

WordNet sense 2 (estrangement from god):

sinfulness, wickedness

WordNet sense 3 (commit a faux pas or a fault or make a serious mistake):

blunder, goof

WordNet sense 4 (commit a sin; violate a law of God or a moral law):

transgress, trespass

WordNet sense 5 (violent and excited activity):

hell

WordNet sense 6 (an act that is regarded by theologians as a transgression of God's will):

sinning