WordNet sense 1 (doomed to extinction):

sunk, washed-up, ruined, done for

WordNet sense 2 (not successful; having failed or having an unfavorable outcome):

unsuccessful

WordNet sense 3 (not closed or secured):

unfastened

WordNet sense 4 (thrown into a state of disorganization or incoherence):

unstuck

WordNet sense 5 (lacking order or methodical arrangement or function):

disorganized, disorganised

WordNet sense 6 (not brought to an end or conclusion):

unfinished