WordNet sense 1 (any materials unused and rejected as worthless or unwanted):

waste material, waste matter, waste product

WordNet sense 2 (an uninhabited wilderness that is worthless for cultivation):

barren, wasteland

WordNet sense 3 (the trait of wasting resources):

wastefulness, thriftlessness

WordNet sense 4 (spend thoughtlessly; throw away):

blow, squander

WordNet sense 5 (run off as waste):

run off

WordNet sense 6 (get rid of (someone who may be a threat) by killing):

liquidate, neutralize, neutralise, knock off, do in

WordNet sense 7 (located in a dismal or remote area; desolate):

desert, godforsaken, wild, desert

WordNet sense 8 (unfavorable to life or growth):

inhospitable

WordNet sense 9 ((law) reduction in the value of an estate caused by act or neglect):

permissive waste

WordNet sense 10 (spend extravagantly):

consume, ware

WordNet sense 11 (useless or profitless activity; using or expending or consuming thoughtlessly or carelessly):

dissipation

WordNet sense 12 (lose vigor, health, or flesh, as through grief):

languish, pine away

WordNet sense 13 (cause to grow thin or weak):

emaciate, macerate

WordNet sense 14 (devastate or ravage):

desolate, devastate, ravage, scourge, desolate, lay waste to

WordNet sense 15 (waste away):

rot