WordNet sense 1 (space for movement):

room

WordNet sense 2 (a line leading to a place or point):

direction

WordNet sense 3 (how something is done or how it happens):

fashion, manner, mode, style

WordNet sense 4 (a course of conduct):

path, way of life

WordNet sense 5 (how a result is obtained or an end is achieved):

agency, means

WordNet sense 6 (to a great degree or by a great distance; very much (`right smart' is regional in the United States)):

right smart