WordNet sense 1 (of the material world):

temporal

WordNet sense 2 (concerned with the world or worldly matters):

mundane, terrestrial

WordNet sense 3 (marked by materialism):

materialistic, worldly-minded

WordNet sense 4 (very sophisticated especially because of surfeit; versed in the ways of the world):

blase, blasé, blasé

WordNet sense 5 (not sacred or concerned with religion):

profane