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Synonyms for Castrate (same or very similar meaning)

WordNet sense 1 (deprive of strength or vigor):

WordNet sense 2 (edit by omitting or modifying parts considered indelicate):
bowdlerize, expurgate, shorten, bowdlerise

WordNet sense 3 (remove the testicles of a male animal):
demasculinise, demasculinize

WordNet sense 4 (remove the ovaries of):
alter, neuter, spay

From the ODE community, based on WordNetadd/edit