WordNet sense 1 (converted or adapted to domestic use):

domestic

WordNet sense 2 (easily handled or managed):

docile, gentle

WordNet sense 3 (no longer in the natural state; developed by human care and for human use):

cultivated

WordNet sense 4 (tamed or trained to obey):

broken

WordNet sense 5 (brought from wildness into a domesticated state):

tame