WordNet sense 1 (in danger of the eternal punishment of hell):

doomed, unsaved, unredeemed

WordNet sense 2 (spiritually or physically doomed or destroyed):

lost

WordNet sense 3 (expletives used informally as intensifiers):

blame, blasted, blessed, darned, infernal, blamed, deuced, goddam, goddamned, blessed, goddamn

WordNet sense 4 (deserving a curse; sometimes used as an intensifier):

cursed, curst

WordNet sense 5 (in a damnable manner):

cursedly, damnably