WordNet sense 1 (make or render deaf):

deafen

WordNet sense 2 ((usually followed by `to') unwilling or refusing to pay heed):

indifferent

WordNet sense 3 (marked by or paying little heed or attention):

heedless, thoughtless, unheeding

WordNet sense 4 (having a hearing loss):

hearing-impaired

WordNet sense 5 (caused to hear poorly or not at all):

deafened