In the less severe "dry" form, accounting for the vast majority of cases, yellowish deposits called drusen accumulate beneath the macula.    From Wordnik.com.  [Fading Of The Light] Reference

In the CAPT, patients with signs of early AMD, defined as 10 or more large deposits known as drusen on the retina and vision 20 / 40 or better, initially completed a.    From Wordnik.com.  [Medlogs - Recent stories] Reference

Called drusen - that appear in the center of the retina, called the macula.    From Wordnik.com.  [latimes.com - News] Reference

And drusen is an early form of macular degeneration.    From Wordnik.com.  [CNN Transcript Sep 28, 2003] Reference

If drusen, the hallmark of AMD, are detected, your doctor may give you an Amsler grid, which looks like a checkerboard.    From Wordnik.com.  [Fading Of The Light] Reference

One other thing is, if a person has developed drusen, does that automatically mean they're going to get macular degeneration?.    From Wordnik.com.  [CNN Transcript Sep 28, 2003] Reference

Just because a patient develops drusen does not mean they will progress to full form -- full blown macular degeneration that significantly affects their vision.    From Wordnik.com.  [CNN Transcript Sep 28, 2003] Reference

No CD63 labeling was seen in the drusen from any age-matched control (n = 10).    From Wordnik.com.  [PLoS ONE Alerts: New Articles] Reference

When age was considered, men and women had approximately the same number of drusen.    From Wordnik.com.  [Medindia Health News] Reference

The presence and severity of drusen-yellow or white deposits in the retina, an early sign of.    From Wordnik.com.  [Medindia Health News] Reference

This type is much more common and is characterized by drusen and loss of pigment in the retina.    From Wordnik.com.  [American Chronicle] Reference

The proteins found in drusen are an admixture of blood proteins, extracellular proteins and intracellular proteins.    From Wordnik.com.  [PLoS ONE Alerts: New Articles] Reference

We found that Atg5, an autophagy marker, was present in drusen in the retina of normal old eyes and old eyes with AMD.    From Wordnik.com.  [PLoS ONE Alerts: New Articles] Reference

"It's the debris of broken up retinal cells, some of which is caused by this cycle, that is deposited as drusen," Okemefuna said.    From Wordnik.com.  [Science Blog] Reference

Individuals with a diagnosed drusen (early AMD) should check with their eye care professional to see if the test is right for them.    From Wordnik.com.  [Marketwire - Breaking News Releases] Reference

The dry form of AMD, which is characterized by drusen in the macula, is more common and accounts for about 85 to 90\% of patients with AMD.    From Wordnik.com.  [PLoS ONE Alerts: New Articles] Reference

We have investigated the conditions and pathways by which intracellular proteins in the RPE become extracellular and, perhaps, end up in drusen.    From Wordnik.com.  [PLoS ONE Alerts: New Articles] Reference

Although some of the molecular components of drusen are known, there is no understanding of the cell biology that leads to the formation of drusen.    From Wordnik.com.  [PLoS ONE Alerts: New Articles] Reference

Furthermore, age-related changes in cellular functions of the RPE may lead to release of intracellular proteins that contribute to the formation of drusen.    From Wordnik.com.  [PLoS ONE Alerts: New Articles] Reference

The formation of drusen, an extracellular, amorphous deposit of material on Bruch's membrane in the macula of the retina, occurs early in the course of the disease.    From Wordnik.com.  [PLoS ONE Alerts: New Articles] Reference

drusen were present in the macula-the area in the retina responsible for sharp vision-in 63.3 percent of the participants, and the frequency of drusen increased with age.    From Wordnik.com.  [Medindia Health News] Reference

"The CAPT data did not support a large effect for statins in decreasing advanced AMD risk in patients who already had large drusen in both eyes," said lead researcher Maureen G. Maguire.    From Wordnik.com.  [Health News from Medical News Today] Reference

"The earliest hallmark of AMD is the appearance of protein, lipid and zinc deposits under the retinal pigment epithelial cells," he said, adding that the yellowish deposits, usually discovered by an ophthalmologist, are commonly known as "drusen.".    From Wordnik.com.  [Science Blog] Reference

"The CAPT data did not support a large effect for statins in decreasing advanced AMD risk in patients who already had large drusen in both eyes," said lead researcher Maureen G. Maguire, PhD, Department of Ophthalmology, University of Pennsylvania.    From Wordnik.com.  [PhysOrg.com - latest science and technology news stories] Reference

The scientists, led by Dr. Jayakrishna Ambati, associate professor of ophthalmology at the university, found that people with "dry" macular degeneration are more likely to progress to the potentially blinding "wet" form when their drusen contain certain chemical components known as C3 and C5.    From Wordnik.com.  [Breaking News: CBS News] Reference

Dr. Kameran Lashkari, from Harvard Medical School's Schepens Eye Research Institute, will provide highlights into research at Harvard involving blood factors surrounding chronic inflammation in the back of the eye that induces drusen, yellowish deposit that is a sign of age-related macular degeneration.    From Wordnik.com.  [marconews.com Stories] Reference

We found that exosome markers, CD63, CD81, LAMP2, were present in drusen from AMD patients (.    From Wordnik.com.  [PLoS ONE Alerts: New Articles] Reference

In donors with AMD, a cluster of Atg5 immunoreactivity was present in the large drusen found in the sub-RPE space (.    From Wordnik.com.  [PLoS ONE Alerts: New Articles] Reference

Among patients who had bilateral large drusen, use of the cholesterol-lowering medications was not associated with a higher or lower risk of progressing to advanced disease (RR 1.15.    From Wordnik.com.  [MedPageToday.com - medical news plus CME for physicians] Reference

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