Hydrogen peroxide attacks an enzyme called tyrosinase, which starts the production of melanin. From Wordnik.com. [COSMOS magazine - The science of everything] Reference
It works by blocking the enzyme tyrosinase inside the melanocytes that makes melanin. From Wordnik.com. [Simple Skin Beauty] Reference
It is an essential element, being part of enzymes like tyrosinase, cytochrome oxidase, etc. From Wordnik.com. [Chapter 13] Reference
The first step of the synthetic pathway for both eumelanins and pheomelanins is mediated by tyrosinase. From Wordnik.com. [Think Progress » Buchanan: Americans Should Consider Allowing Only White Immigrants] Reference
It includes tyrosinase activity (melanin is synthesed from tyrosine), DOPA production (used in threatment of Parkinson disease and depression) and in many other metabolytical pathways. From Wordnik.com. [Just call him/her Ol’ Blue Eyes] Reference
Not only that, but high levels of hydrogen peroxide and low levels of MSR A and B disrupt the formation of yet another enzyme, called tyrosinase, that leads to the production of hair pigments. From Wordnik.com. [The old gray hair, she ain’t what she used to be] Reference
It was a surprise that the T cells of some melanoma patients recognized antigens in normal proteins -- a situation that verges on an auto-immune response; Boon's group has found two of these antigens in melanoma, Melan-A and tyrosinase. From Wordnik.com. [Vaccinating Against Cancer] Reference
The effects of light and tyrosinase during sclerotium development in Sclerotium rolfsii Sacc. From Wordnik.com. [xml's Blinklist.com] Reference
A three-dimensional model of mammalian tyrosinase active site accounting for loss of function mutations. From Wordnik.com. [innovations-report] Reference
"In gluten-free research a number of ingredients are being used to this effect, such as transglutaminase, tyrosinase and laccase.". From Wordnik.com. [FoodNavigator RSS] Reference
SCIB1 is designed to stimulate a powerful immune response against the melanoma antigen tyrosinase related protein 2 (TRP-2), a well-known melanoma target. From Wordnik.com. [Marketwire - Breaking News Releases] Reference
The St George's, University of London team and colleagues from the University of Colorado School of Medicine have discovered that a common variant in the gene tyrosinase (TYR) increases. From Wordnik.com. [THE MEDICAL NEWS] Reference
Genetic testing for tyrosinase and other genes in the study could determine the best candidates for melanoma-fighting immunotherapies, such as interleukin 2 and various vaccines, he noted. From Wordnik.com. [Social Security Reports, News and Informaion] Reference
Further complicating matters, the high levels of hydrogen peroxide and low levels of MSR A and B, disrupt the formation of an enzyme, tyrosinase, that leads to the production of melanin in hair follicles. From Wordnik.com. [IrishHealth.com] Reference
Apples and other produce (e.g., pears, bananas, peaches, potatoes) contain an enzyme (called polyphenol oxidase or tyrosinase) that reacts with oxygen and iron-containing phenols that are also found in the apple. From Wordnik.com. [Yahoo! Answers: Latest Questions] Reference
Arctostaphylos uva-ursi (Bearberry) that is able to both inhibit tyrosinase activity and reduce melanin concentration in cells. e.g. for use in anti-age skin care products to prevent age spots and irregular skin pigmentation. From Wordnik.com. [CosmeticsDesign RSS] Reference
Specifically, amassed and highly destructive reactive oxygen species (ROS), often referred to as "free radicals" or "oxidants", damage melanocytes, the cells that produce melanin, because the responsible enzyme, tyrosinase, is inactivated by the high levels of hydrogen peroxide. From Wordnik.com. Reference
In addition, preclinical data indicate that OXi4503 is metabolized by oxidative enzymes (e.g., tyrosinase and peroxidases), which are elevated in many solid tumors and tumor white blood cell infiltrates, to an orthoquinone chemical species that has direct cytotoxic effects on tumor cells. From Wordnik.com. [News] Reference
In addition, preclinical data indicates that OXi4503 is metabolized by oxidative enzymes (e.g., tyrosinase and peroxidases), which are elevated in many solid tumors and tumor white blood cell infiltrates, to an orthoquinone chemical species that has direct cytotoxic effects on tumor cells. From Wordnik.com. [News] Reference
DCT, also known as Tyrosine-related protein-2) are mostly known for conferring phenotypic changes along the yellow-brown axis, and the three genes all belong to the tyrosinase family. From Wordnik.com. [PLoS ONE Alerts: New Articles] Reference
tyrosinase, 208. From Wordnik.com. [Simple Skin Beauty] Reference
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