It is a once-in-a-lifetime kind of crusade for Oprah.    From Wordnik.com.  [CNN Transcript Sep 9, 2007] Reference

And it was an adventure, it was a once-in-a-lifetime thing.    From Wordnik.com.  [CNN Transcript - Larry King Live: Paula Jones Discusses Why She's Posing for 'Penthouse' - October 24, 2000] Reference

"I feel like this is probably lucky, once-in-a-lifetime stuff.".    From Wordnik.com.  ['Rally to Restore Sanity' to meet 'March to Keep Fear Alive;' Reddit users talk about starting the campaign] Reference

And it's kind of a once-in-a-lifetime opportunity here, gentlemen.    From Wordnik.com.  [CNN Transcript Mar 22, 2003] Reference

It was a once-in-a-lifetime moment that I wish was caught on video.    From Wordnik.com.  [Mark Horvath: Interview with Robert Egger of D.C. Central Kichten and James S. Withers of Operation Safety Net] Reference

Mayor Richard Daley has called it a once-in-a-lifetime opportunity.    From Wordnik.com.  [CNN Transcript Oct 1, 2009] Reference

And so as he mentioned, it's a once-in-a-lifetime dream to win a U.S.    From Wordnik.com.  [CNN Transcript Jun 14, 2008] Reference

College is full of peculiar norms and once-in-a-lifetime entitlements.    From Wordnik.com.  [Liz O'Neill: 8 Things That Stop Being Cool After College] Reference

DALEY: Oh, it's been a once-in-a-lifetime experience, Larry, believe me.    From Wordnik.com.  [CNN Transcript - Larry King Live: Gore and Bush Campaigns Clashing Over Florida Vote Tally; Florida Secretary of State Denies Counties' Requests for Manual Recounts - November 15, 2000] Reference

New Mexico Governor Bill Richardson calls him a once-in-a-lifetime leader.    From Wordnik.com.  [CNN Transcript Mar 21, 2008] Reference

Did you know that a once-in-a-lifetime planetary alignment will occur tonight?.    From Wordnik.com.  [Unexpected Flying Objects] Reference

And the stars speak out to SHOWBIZ TONIGHT about this once-in-a-lifetime moment.    From Wordnik.com.  [CNN Transcript Jan 21, 2009] Reference

I mean, experiences like this are a once-in-a-lifetime, so I couldn't pass that up.    From Wordnik.com.  [CNN Transcript Jan 17, 2009] Reference

"This is a once-in-a-lifetime moment to do the thing she cares about most," Tyagi said.    From Wordnik.com.  [Elizabeth Warren, likely to head new consumer agency, provokes strong feelings] Reference

Today had been set aside as a once-in-a-lifetime event, the birth of their first child.    From Wordnik.com.  [CNN Transcript Feb 10, 2003] Reference

GUTIERREZ: It was literally a once-in-a-lifetime moment for Ona Lea and Leane Mustonen.    From Wordnik.com.  [CNN Transcript Feb 3, 2006] Reference

A long-time Clinton ally, he says this is a once-in-a-lifetime opportune for this country.    From Wordnik.com.  [CNN Transcript Mar 23, 2008] Reference

Astronomers have been preparing for this week like players before a once-in-a-lifetime game.    From Wordnik.com.  [Mysteries Of The Sun] Reference

His tastes were pretty simple, and simple just didn't cut it for this once-in-a-lifetime event.    From Wordnik.com.  [Putting the Fun in Funeral] Reference

Finding a plumber who will return your phone calls within 72 hours is a once-in-a-lifetime thing.    From Wordnik.com.  [There’s No Place Like Home] Reference

The music, along with the iconic films, is a once-in-a-lifetime experience for musicians and the audience.    From Wordnik.com.  [Fern Siegel: Stage Door: The Lord of the Rings: Two Towers] Reference

And state of emergency in Upstate New York caught off guard by what is being called a once-in-a-lifetime storm.    From Wordnik.com.  [CNN Transcript Oct 13, 2006] Reference

BLAUSER: Well, I saw it as a once-in-a-lifetime opportunity to help the children of Iraq who don't have a voice.    From Wordnik.com.  [CNN Transcript Oct 30, 2009] Reference

(BEGIN VIDEOTAPE) (voice-over): Federal officials have said over and over, Katrina was a once-in-a-lifetime event.    From Wordnik.com.  [CNN Transcript Sep 3, 2005] Reference

Like high, low, media, it brought us all together but it ` s unfortunate that it can only happen once-in-a-lifetime.    From Wordnik.com.  [CNN Transcript Dec 23, 2009] Reference

UNIDENTIFIED FEMALE: This is a once-in-a-lifetime opportunity for my girls to see a live example of what they can do.    From Wordnik.com.  [CNN Transcript Jan 24, 2009] Reference

It's being called a once-in-a-lifetime storm, and Hurricane Katrina is giving much of the Gulf Coast a brutal beating.    From Wordnik.com.  [CNN Transcript Aug 29, 2005] Reference

Here is a chance to have a once-in-a-lifetime experience, an experience that I will carry with me the rest of my life.    From Wordnik.com.  [CNN Transcript - Saturday Morning News: Russia Hosts First Crew of International Space Station - September 30, 2000] Reference

And to have that kind of opportunity, these are once-in-a-lifetime moments that take your whole life to be able to experience.    From Wordnik.com.  [Studying And Surfing The Ocean's Monster Waves] Reference

Points can also be credited toward travel packages and a changing roster of activities it calls "once-in-a-lifetime experiences.".    From Wordnik.com.  [Don't Fly Home Without It] Reference

We're pushing forward, though a once-in-a-lifetime disaster, once too many for the victims of the devastating flooding in Georgia.    From Wordnik.com.  [CNN Transcript Sep 22, 2009] Reference

John Allen Lambertville, N. J.Katie Couric is certainly a gifted journalist who has stumbled into a once-in-a-lifetime opportunity.    From Wordnik.com.  [Letters to the Magazine] Reference

There was always a boyfriend to stay with or a once-in-a-lifetime holiday paid by her father in one of his periodical guilt explosions.    From Wordnik.com.  [Life Experience] Reference

ECCLESTON: Cassandra and Anne are two of the more than 8,000 foreign students that come to Perugia for a once-in-a-lifetime experience.    From Wordnik.com.  [CNN Transcript Nov 23, 2007] Reference