This fibrotic replacement of the liver is known as "cirrhosis".    From Wordnik.com.  [Cell damage from toxicity and tissue repair] Reference

Replacement of normal liver cells by fibrotic cells in chronic alcoholics (known as cirrhosis of the liver).    From Wordnik.com.  [Cellular adaptation to toxicity] Reference

The fibrotic scar tissue shores up the damage but it can not replace the function of the lost hepatic tissue.    From Wordnik.com.  [Cell damage from toxicity and tissue repair] Reference

The pancreas of each dog was removed and all were found to be shrivelled, fibrotic, and about one-third the original size.    From Wordnik.com.  [Frederick G. Banting - Nobel Lecture] Reference

And, on the other hand, we know that a very fibrotic live or a very cirrhotic liver is actually very hard to the touch, almost rock-hard.    From Wordnik.com.  [CNN Transcript Dec 20, 2007] Reference

With constant fibrotic change, the liver function is continually diminished so that eventually the liver can no longer maintain homeostasis.    From Wordnik.com.  [Cell damage from toxicity and tissue repair] Reference

At the same time, the alveolar exudate has become fibrotic.    From Wordnik.com.  [Recently Uploaded Slideshows] Reference

Depressed fibrotic scars are very large compared to ice-pick scars.    From Wordnik.com.  [MyLinkVault Newest Links] Reference

Ice-pick scars can develop into depressed fibrotic scars over time.    From Wordnik.com.  [MyLinkVault Newest Links] Reference

The area of fibrotic tissue was quantified by computer software (Quantimet 570, Leica).    From Wordnik.com.  [PLoS ONE Alerts: New Articles] Reference

As the disease progresses, air sacs in the lungs become replaced by fibrotic scar tissue.    From Wordnik.com.  [THE MEDICAL NEWS] Reference

This was confirmed by the specific accumulation of the radiotracer in lung fibrotic lesions.    From Wordnik.com.  [PLoS ONE Alerts: New Articles] Reference

A: Planar thoracic scintigraphy of a rat with fibrotic myocardial infarction: a clear hot-spot.    From Wordnik.com.  [PLoS ONE Alerts: New Articles] Reference

Diegelmann RF, Evans MC (2004) Wound healing: an overview of acute, fibrotic and delayed healing.    From Wordnik.com.  [PLoS ONE Alerts: New Articles] Reference

First, an histochemical analysis was performed on sections of healthy and fibrotic lungs (fig 6A).    From Wordnik.com.  [PLoS ONE Alerts: New Articles] Reference

The results also suggest a broader role for miR-29 in the settings of fibrotic diseases in general.    From Wordnik.com.  [Health News from Medical News Today] Reference

In this study, the collagenase clostridium histolyticum was injected directly into the fibrotic cord.    From Wordnik.com.  [Medlogs - Recent stories] Reference

Stromedix, Inc., a biotechnology company focused on innovative therapies for fibrosis and fibrotic o.    From Wordnik.com.  [THE MEDICAL NEWS] Reference

Promedior, Inc., a leader in the development of novel therapeutics for the treatment of fibrotic dis.    From Wordnik.com.  [THE MEDICAL NEWS] Reference

Preclinical and in-vitro evidence had shown that pirfenidone has both anti-fibrotic and anti-inflammatory effects.    From Wordnik.com. Reference

Backgroud Gluteal muscle contracture (GMC) is a multi-factor human chronic fibrotic disease of the gluteal muscle.    From Wordnik.com.  [BioMed Central - Latest articles] Reference

EMT, which is characterized by a change in cells from adherent to mobile, has been implicated in fibrotic diseases.    From Wordnik.com.  [EurekAlert! - Breaking News] Reference

There are different types of acne scars and the main types are: ice-pick scars, depressed fibrotic scars and soft scars.    From Wordnik.com.  [MyLinkVault Newest Links] Reference

The researchers said VP is different from fibrotic, calcified plaque that grows gradually until a lesion occludes an artery.    From Wordnik.com.  [Latest News - UPI.com] Reference

These cells are derived from the differentiation of fibroblasts, under the influence of pro-fibrotic factors such as TGF-beta.    From Wordnik.com.  [PLoS ONE Alerts: New Articles] Reference

B: Planar and tomographic (frontal and sagittal views) thoracic images of a rat with a fibrotic myocardial infarction: a hot-spot.    From Wordnik.com.  [PLoS ONE Alerts: New Articles] Reference

"Unlike a typical plug repair which can cause a hard fibrotic knot, these excised implants are soft and pliable, says Dr. Amato.".    From Wordnik.com.  [Medgadget] Reference

Strong up-regulation of these proteins in fibrotic muscle was confirmed by immunohistochemical staining and Western blot analysis.    From Wordnik.com.  [BioMed Central - Latest articles] Reference

Scintigraphic molecular imaging with collagelin provides high resolution, and good contrast between the fibrotic scars and healthy tissues.    From Wordnik.com.  [PLoS ONE Alerts: New Articles] Reference

These results indicate that EMT may be at least partially responsible for fibrotic eye damage in patients following bone marrow transplantation.    From Wordnik.com.  [THE MEDICAL NEWS] Reference

To further investigate the presence and localisation of KGF in the fibrotic lung, we investigated KGF protein levels by immunohistochemistry and ELISA.    From Wordnik.com.  [PLoS ONE Alerts: New Articles] Reference

Specific accumulation of radiolabeled collagelin provided good contrast molecular imaging of the fibrotic scar, clearly distinguishable from the healthy myocardium.    From Wordnik.com.  [PLoS ONE Alerts: New Articles] Reference

Transforming growth factor (TGF) - beta1 and - beta2 are thought to play an important role in fibrogenesis, while TGF-beta3 is believed to have an anti-fibrotic function.    From Wordnik.com.  [BioMed Central - Latest articles] Reference

Stiffer substrates, the kind that mimic fibrotic scarring, produce heart cells that overstrain themselves and fail to stitch their proteins together to form heart muscle.    From Wordnik.com.  [PhysOrg.com - latest science and technology news stories] Reference

This technology treats complex cardiovascular conditions by vaporizing lipid-based, calcified and fibrotic plaque, saphenous vein graft disease, and neointimal hyperplasia.    From Wordnik.com.  [News for NBC13.com] Reference

Moreover, we detected a significant increase in the mitogenic activity of alveolar type II cells in those mice with proliferating type II cells associated with fibrotic foci.    From Wordnik.com.  [PLoS ONE Alerts: New Articles] Reference

Previous studies have shown that early but not late delivery of MSCs can attenuate the inflammatory response to bleomycin induced lung damage and ameliorate the fibrotic effects.    From Wordnik.com.  [PLoS ONE Alerts: New Articles] Reference