The older group also had fewer apoptotic cells, an important discovery. From Wordnik.com. [Father's Age as a Risk Factor for Autism] Reference
The cell disintegrates into fragments referred to as "apoptotic bodies". From Wordnik.com. [Cell damage from toxicity and tissue repair] Reference
These apoptotic bodies and the organelles are phagocytized by adjacent cells and local macrophages without initiation of an inflammatory response as is seen in necrosis. From Wordnik.com. [Cell damage from toxicity and tissue repair] Reference
The observed changes in spermatozoal expression of transcriptional and apoptotic genes may result in poor seminal parameters found in boys with a history of cryptorchidism. From Wordnik.com. [Urology Division Research] Reference
Ramasubbu, Sankararamakrishnan (2008) Anti-apoptotic hBcl. From Wordnik.com. [PLoS ONE Alerts: New Articles] Reference
OPN overexpressing cells have reduced apoptotic cell death both. From Wordnik.com. [PLoS ONE Alerts: New Articles] Reference
BCL2 is best known as a multifunctional anti-apoptotic protein. From Wordnik.com. [Naturejobs - All Jobs] Reference
Maelfait J, Beyaert R (2008) Non-apoptotic functions of caspase-8. From Wordnik.com. [PLoS ONE Alerts: New Articles] Reference
Cancer cells frequently and possibly invariably possess apoptotic defects. From Wordnik.com. [The Earth Times Online Newspaper] Reference
It is reported that IL-2 has an anti-apoptotic effect on activated T cells. From Wordnik.com. [PLoS ONE Alerts: New Articles] Reference
And by inhibiting it's growth, we're increasing the cells's apoptotic function. From Wordnik.com. [innovations-report] Reference
The bars indicate the fraction of apoptotic cells for each experimental condition. From Wordnik.com. [PLoS ONE Alerts: New Articles] Reference
The percentage of cells with sub-G0-G1 DNA content was counted as apoptotic cells. From Wordnik.com. [PLoS ONE Alerts: New Articles] Reference
D. TUNEL immunostaining showing increased apoptotic nuclei (arrows) in livers post GCV. From Wordnik.com. [PLoS ONE Alerts: New Articles] Reference
Yersinia, indicating that YopJ/YopP did not directly activate the PMN apoptotic pathway. From Wordnik.com. [PLoS ONE Alerts: New Articles] Reference
The work provides the first evidence that a lipid can initiate the suicidal, or apoptotic, response in cells. From Wordnik.com. Reference
Mechanistically, OPN has been shown to counteract the pro-apoptotic effect of serum starvation in two-dimensional. From Wordnik.com. [PLoS ONE Alerts: New Articles] Reference
Only B16F10 melanoma cells exhibit a significantly high level of apoptotic cells (40. 5%±2.5) when cultured in CM. From Wordnik.com. [PLoS ONE Alerts: New Articles] Reference
Salvesen GS, Yuan J, Wagner G (1999) Solution structure of BID, an intracellular amplifier of apoptotic signaling. From Wordnik.com. [PLoS ONE Alerts: New Articles] Reference
+ T cell activation was a result of anti-apoptotic effect, we compared the cell death rates between stimulated CD8. From Wordnik.com. [PLoS ONE Alerts: New Articles] Reference
Note that more apoptotic nuclei are present in MiaPaCa-2 vector control and RAA compared to OPN-A overexpression (A). From Wordnik.com. [PLoS ONE Alerts: New Articles] Reference
In the RESMAC population, approximately one-tenth of monocyte-like cells and one-third of vacuolized cells were apoptotic. From Wordnik.com. [BioMed Central - Latest articles] Reference
JNK can phosphorylate Jun, a member of the AP1 transcriptional regulator, thus eliciting a JNK-dependent apoptotic cascade. From Wordnik.com. [PLoS ONE Alerts: New Articles] Reference
Cancer cells often become dependent on one or more anti-apoptotic proteins to avoid death while continuing to proliferate. From Wordnik.com. [EurekAlert! - Breaking News] Reference
Immunoprecipitation experiments revealed that MCL-1 and BCL-2 both work by sequestering the same two pro-apoptotic targets. From Wordnik.com. [EurekAlert! - Breaking News] Reference
Moreover, a higher percentage of apoptotic cells in INFMAC was detected during all time points after PBS in contrast to LPS. From Wordnik.com. [BioMed Central - Latest articles] Reference
It is well accepted that acquired resistance to apoptotic and/or growth arrest signals plays a major role in tumor progression. From Wordnik.com. [PLoS ONE Alerts: New Articles] Reference
XL protein in complex with BH3 peptides of pro-apoptotic Bak, Bad, and Bim proteins: comparative molecular dynamics simulations. From Wordnik.com. [PLoS ONE Alerts: New Articles] Reference
Areas of necrosis, acidophilic bodies, necrosis and apoptotic bodies were also featured in these livers but were absent from vTK −. From Wordnik.com. [PLoS ONE Alerts: New Articles] Reference
Magnelli L, Chiarugi VP, Israel MA (1996) Herpes simplex virus thymidine kinase/ganciclovir-mediated apoptotic death of bystander cells. From Wordnik.com. [PLoS ONE Alerts: New Articles] Reference
Tsukamoto A (1995) Gene therapy of hepatoma: bystander effects and non-apoptotic cell death induced by thymidine kinase and ganciclovir. From Wordnik.com. [PLoS ONE Alerts: New Articles] Reference
The paucity of TUNEL-positive apoptotic MH and HH likely precludes their involvement in vTK/GCV-induced hepatic failure in chimeric mice. From Wordnik.com. [PLoS ONE Alerts: New Articles] Reference
Macrophage clearance of apoptotic PMNs prevents release of cytotoxic granule components and limits subsequent damage to surrounding healthy tissues. From Wordnik.com. [PLoS ONE Alerts: New Articles] Reference
However, the detailed pathways and mechanisms by which OPN mediates its anti-apoptotic effect can be different for various cell types and stressors. From Wordnik.com. [PLoS ONE Alerts: New Articles] Reference
In this context, apoptotic pathways provide exciting molecular targets for new therapeutic agents to specifically promote apoptosis of cancer cells. From Wordnik.com. [The Earth Times Online Newspaper] Reference
Tsuda M, Kiso M, Saga Y (2008) Nanos3 maintains the germ cell lineage in the mouse by suppressing both Bax-dependent and - independent apoptotic pathways. From Wordnik.com. [PLoS ONE Alerts: New Articles] Reference
Further, TLR3 is critical for protection against severe herpes infections and implicated as a target of viral anti-apoptotic genes during human monocytic cell infections. From Wordnik.com. [PLoS ONE Alerts: New Articles] Reference
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