After 10 days of ALI culture, cells demonstrated mucociliary differentiation, and were infected with. From Wordnik.com. [PLoS ONE Alerts: New Articles] Reference
In Xenopus, expression of a dn-fgfr1 results in shorter monocilia in the gastrocoel roof plate that control left-right patterning and in shorter multicilia in external mucociliary epithelium. From Wordnik.com. [Naturejobs - All Jobs] Reference
Mutations in CFTR cause CF, and the initial pathophysiology of the lung disease involves defective ion transport, dehydration of the mucous layer, and reduced mucociliary and cough clearance. From Wordnik.com. [PLoS ONE Alerts: New Articles] Reference
Previous preclinical and exploratory clinical studies suggest that therapeutic surfactants may improve mucociliary clearance, thereby potentially preventing further compromise of lung function. From Wordnik.com. [Discovery Labs Announces Presentation & Key Results of Phase 2a Study of Aerosolized KL4 Surfactant in Cystic Fibrosis at the North American Cystic Fibrosis Conference - Yahoo! Finance] Reference
The bronchioles of the murine lung are lined by a simple columnar epithelium composed of ciliated, Clara, and goblet cells that together mediate barrier function, mucociliary clearance and innate host defense, vital for pulmonary homeostasis. From Wordnik.com. [Elites TV] Reference
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