Purkinje neurons of different ages are endowed with intrinsic stage-specific competence for neuritic growth. From Wordnik.com. [PLoS ONE Alerts: New Articles] Reference
One GSM was tested in a transgenic mouse model designed to overproduce A-beta 42 and 40 and develop neuritic plaques. From Wordnik.com. [PhysOrg.com - latest science and technology news stories] Reference
We demonstrate that these compounds inhibit Aβ-induced neuronal death, neuritic degeneration and activation of calpain / cdk5. From Wordnik.com. [PLoS ONE Alerts: New Articles] Reference
Aberrant activation of the cdk5, GSK3β and JNK kinases leads to tau hyperphosphorylation, cytoskeletal disruption and neuritic dystrophy. From Wordnik.com. [PLoS ONE Alerts: New Articles] Reference
It was also interesting to note that caspase-4 expression increased most dramatically with the presence of even just a few neuritic plaques. From Wordnik.com. [PLoS ONE Alerts: New Articles] Reference
For neuritic dystrophy assays, 150,000-200,000 neurons per well were seeded into 6-well plates containing 25 mm coverslips and matured 21-22 days. From Wordnik.com. [PLoS ONE Alerts: New Articles] Reference
The distinct neuritic growth pattern of embryonic and postnatal neurons could be consequent to the distinct cellular environment of the two cultures. From Wordnik.com. [PLoS ONE Alerts: New Articles] Reference
On the other hand, the specific neuritic patterns could be determined by the different environmental conditions provided by embryonic and postnatal cultures. From Wordnik.com. [PLoS ONE Alerts: New Articles] Reference
The presence of a brain lesion on MRI at the time of optic neuritic affects prognosis at the risk of multiple sclerosis at 10 years is 56\% with a brain lesion. From Wordnik.com. [Citizendium, the Citizens' Compendium - Recent changes [en]] Reference
Previous studies on dissociated PCs indicate that exposure to specific substances can stimulate neuritic extension, but do not affect the overall growth pattern. From Wordnik.com. [PLoS ONE Alerts: New Articles] Reference
Expression of the indicated genes in BA28 / 36 was assessed by qPCR, comparing expression in individuals with differing degrees of neocortical neuritic plaque density. From Wordnik.com. [PLoS ONE Alerts: New Articles] Reference
Hippocampal neurons kept in vitro for ≥ 3 weeks express mature isoforms of tau protein, and when exposed to Aβ primarily demonstrate neuritic dystrophy rather than death. From Wordnik.com. [PLoS ONE Alerts: New Articles] Reference
These cultures reveal that embryonic and postnatal neurons are endowed with intrinsic stage-specific neuritic growth properties that match their neuritogenic pattern in vivo. From Wordnik.com. [PLoS ONE Alerts: New Articles] Reference
Previous studies on retinal ganglion neurons indicate that the switch from elongating to arborizing neuritic growth is tightly linked to the initiation of dendritogenic processes. From Wordnik.com. [PLoS ONE Alerts: New Articles] Reference
Decreased expression of LRP1 and NYGGF4 over disease, evident with the presence of even moderate numbers of neuritic plaques, suggests that LRP1-NYGGF4 is a system altered early in disease. From Wordnik.com. [BioMed Central - Latest articles] Reference
Chronic daily administration for 7 months led to significant reduction in both diffuse and neuritic plaques, without the GI-related side effects found with GSI compounds, according to the paper in. From Wordnik.com. [Business Wire Travel News] Reference
And those were consistent with symptoms of alodinea, increased neuritic pain, or spreading of the area of anesthesia or dysfunction, we have a protocol to intervene, surgically to reduce the swelling in the cord. From Wordnik.com. [Geron CEO Discusses Q3 2010 Results - Earnings Call Transcript -- Seeking Alpha] Reference
Therefore, when placed in vitro PCs spontaneously reinitiate neuritic development according to a preferential elongating or arborizing pattern that reflects the embryonic or postnatal age when they were dissociated. From Wordnik.com. [PLoS ONE Alerts: New Articles] Reference
Amacrine cell-derived signals dampen neuritic lengthening and stimulate dendritic extension, leading to the hypothesis that initiation of dendritogenesis restricts the endogenous neuronal inclination for neuritic growth. From Wordnik.com. [PLoS ONE Alerts: New Articles] Reference
Indeed, while exposure to the postnatal environment stimulates the growth of embryonic axons without modifying their phenotype, contact-mediated signals derived from granule cells specifically induce arborising growth and modulate the dynamics of neuritic elongation. From Wordnik.com. [PLoS ONE Alerts: New Articles] Reference
Taking advantage of the distinct time-windows in which Purkinje cells carry out elongating or arborizing axonal growth, we examined their neuritic development in dissociated cultures prepared at the relevant ontogenetic stages (respectively embryonic day 17, E17, and postnatal day 0, P0). From Wordnik.com. [PLoS ONE Alerts: New Articles] Reference
Figure 7B), but displayed a clear-cut switch towards arborizing neuritic growth (Figure 4D). From Wordnik.com. [PLoS ONE Alerts: New Articles] Reference
Table 2, in both conditions the relative frequencies of these neuritic phenotypes were similar for isolated PCs or for PCs in contact with other cells (Chi square or Fisher exact tests always P >. From Wordnik.com. [PLoS ONE Alerts: New Articles] Reference
To live with him with those neuritic pangs. From Wordnik.com. [Toward the Gulf] Reference
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