This condition—called acanthosis nigricans—is an early sign of metabolic syndrome, which is associated with high blood pressure plus elevated levels of blood lipids and blood sugar. From Wordnik.com. [You: On a Diet] Reference
"We screen children for a rash on the back of the neck called acanthosis nigricans, a hyper pigmented, raised rash on the back of the neck that occurs in children and adults who are obese and have insulin resistance," Neal said. From Wordnik.com. Reference
PCOS may also be associated with obesity, infertility, pre - or type 2 diabetes, and a skin condition known as acanthosis nigricans (AN), which causes darkened, velvety patch of skin, commonly on the nape of the neck, armpits, inner thighs or under the breasts. From Wordnik.com. [News] Reference
See also specific exercise acanthosis nigricans, 124. From Wordnik.com. [You: On a Diet] Reference
Having acanthosis nigricans dark, thickened skin around you neck or armpits. From Wordnik.com. [Could you have diabetes and not know it?] Reference
Having acanthosis nigricans (dark, thickened skin around you neck or armpits). From Wordnik.com. [Could you have diabetes and not know it?] Reference
She had long suspected her only child, who she says always has been overweight, might also have the disease, because he had an area of darkened skin on the back of his neck, a marking doctors call acanthosis nigricans. From Wordnik.com. [Diabetes strikes younger and younger] Reference
Advised to apply tretinoin on acanthosis nigracans. From Wordnik.com. [Recently Uploaded Slideshows] Reference
Chordomata b. acanthosis occurs a. of the base of the skull. From Wordnik.com. [Recently Uploaded Slideshows] Reference
General: Thyroid disease, Cushing syndrome, Signs of virilization, Signs of insulin resistance e.g. acanthosis nigricans. From Wordnik.com. [Recently Uploaded Slideshows] Reference
Dermatologist, etc. (As needed: stress test, micro / macrovascular disease, gastroparesis, colorectal exam, acanthosis nigricans). From Wordnik.com. [Fanatic Cook] Reference
H/E and Toluidin blue staining shows acanthosis, hyperkeratosis, spongiosis, epidermoid cysts and massive infiltration of mast cells in the dermis of the N1N2K5 derived graft. From Wordnik.com. [PLoS ONE Alerts: New Articles] Reference
Now his two sons, 8-year-old John Carlos and 9-year-old Ruben Jr., show some of the telltale signs - the dark coloring of the fold at the back of the neck, or acanthosis nigricans. From Wordnik.com. [Highland Park TX | outside.in] Reference
Alternatively, a more complicated diagnostic test can be used directly at the first antenatal visit in high-risk patients (for example in those with polycystic ovarian syndrome or acanthosis nigricans). From Wordnik.com. [xml's Blinklist.com] Reference
Representative histology of skin demonstrates cutaneous acanthosis and hyperkeratosis in GVHD controls (iii) and minimal skin pathology in recipients of Tregs (iv). doi: 10.1371/journal. pbio.1000302.g005. From Wordnik.com. [PLoS Biology: New Articles] Reference
Pathologically the first change noted in the epidermis is thought to be an acanthosis, followed by epithelial atrophy, and a hyperkeratosis, intercellular edema, and colloid degeneration of the prickle cells. From Wordnik.com. [Essentials of Diseases of the Skin Including the Syphilodermata Arranged in the Form of Questions and Answers Prepared Especially for Students of Medicine] Reference
Slide 21: C. PERIPHERAL •Idiopathic: Regular ovulation & normal androgen levels •Insulin resistance - HAIRAN syndrome: HyperAndrogenic Insulin-Resistant acanthosis Nigricans - 5H syndrome acanthosis nigricans. From Wordnik.com. [Recently Uploaded Slideshows] Reference
Anecdote not being the singular of data, I did have high-dose niacin prescribed; it had an excellent effect on lipids; it had to be stopped because it caused acanthosis nigricans with substantial skin pain and bleeding. From Wordnik.com. [Citizendium, the Citizens' Compendium - Recent changes [en]] Reference
Exclude Non-classical 17-hydroxylase deficiency can look like PCOS HAIRAN - hyperandrogenic insulin resistance and acanthosis nigricans Adrenal tumor Cushing's Prolactin Thyroid Pituitary insufficiency Hypothalamic amenorrhea. From Wordnik.com. [Recently Uploaded Slideshows] Reference
Asterisks indicate enlarged regions of the skin showing acanthosis, hyperkeratosis and spongiosis of the epidermis as well as eosinophil infiltrates (arrows) around dilated blood vessels (bv) in the dermis (n = 8, 4 individual experiments were performed). From Wordnik.com. [PLoS ONE Alerts: New Articles] Reference
Patients also present with acanthosis nigricans (dark velvety pigmentation of the skin) in the axilla, neck or groin, severe insulin resistance, high levels of serum insulin and serum triglycerides and low levels of high-density lipoprotein (HDL) cholesterol. From Wordnik.com. [WN.com - Articles related to Woman dies from bird flu infection in C China] Reference
GVHD control mice uniformly developed a diffuse skin rash and hair loss; skin histology analysis documented cutaneous acanthosis and hyperkeratosis in GVHD controls, but not in Treg recipients (representative histology. From Wordnik.com. [PLoS Biology: New Articles] Reference
K14-TSLP mice exhibit a nearly identical skin phenotype to Notch signaling deficient mice, showing hyperproliferation, acanthosis, spongiosis and hyperkeratosis, as well as mast cell infiltration in the dermis, but normal hair follicles (. From Wordnik.com. [PLoS ONE Alerts: New Articles] Reference
Histological analysis of Notch mutant mice revealed a massive dermal hypercellularity, a complete loss of subcutaneous fat, the presence of numerous hyperproliferative epidermoid cysts in the dermis and a thickened and hyperkeratinized epidermis (acanthosis and hyperkeratosis) (. From Wordnik.com. [PLoS ONE Alerts: New Articles] Reference
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