If the blastomere is aneuploid, this molecular tool, called "fluorescence in situ hybridization," or FISH, will unmask it. From Wordnik.com. [Delayed Childbearing] Reference
It turns out that our cells have been derived utilizing what we call a blastomere technology which means that we have been able to develop those stem cells without any embryo destruction, which somewhat mitigates the issues that have been in the media. From Wordnik.com. [Advanced Cell Technology's CEO Says Markets Are Just Starting to Appreciate the Significance of Their Stem Cell Derived Treatments - Yahoo! Finance] Reference
I think fewer people would be against blastomere research. From Wordnik.com. [Think Progress » GOP Senate candidate compares embryonic stem cell research to ‘what the Nazis did to the Jews.’] Reference
The blastomere technology has been reproduced and peer-reviewed on several occasions. From Wordnik.com. [Barbara Walters' Television Special Highlights Role Advanced Cell Technology's Embryonic Stem Cells Breakthroughs] Reference
In addition to its blastomere research platform, Advanced Cell Technology has made progress on the therapeutic front. From Wordnik.com. [Barbara Walters' Television Special Highlights Role Advanced Cell Technology's Embryonic Stem Cells Breakthroughs] Reference
Size, similarity to extant embryos, regularity, uniformity of blastomere size, and the presence of multiple near-identical exemplars in the same samples. From Wordnik.com. [Taphonomy of fossilized embryos - The Panda's Thumb] Reference
That exchange came to mind this week with news that stem-cell lines can be established from an early human embryo — a blastomere — without destroying it. From Wordnik.com. [Escape Hatch] Reference
Lanza counters this objection by saying that if the blastomere failed to divide, his group would send it off for PGD testing immediately, thereby salvaging the diagnostic procedure. From Wordnik.com. [Scientific Sidestep?] Reference
But other researchers disagree, saying that the removal of the blastomere poses unknown risks to the embryo and in turn, to the life of the child, should the embryo be implanted and continue developing to birth. From Wordnik.com. [Scientific Sidestep?] Reference
The test involves removing one cell, or blastomere, from an eight-cell embryo and exposing the cell to flagged fragments of single-stranded DNA, which bind to the chromosomes and can be viewed, glowing, under a special microscope. From Wordnik.com. [Delayed Childbearing] Reference
In August 2006, Advanced Cell Technology reported in the journal Nature that company scientists had successfully generated hESCs using its blastomere technology, an approach that does not destroy the developmental potential of embryos. From Wordnik.com. [Barbara Walters' Television Special Highlights Role Advanced Cell Technology's Embryonic Stem Cells Breakthroughs] Reference
C. elegans blastomere to distinguish endoderm from mesoderm. From Wordnik.com. [PLoS Biology: New Articles] Reference
We established an hESC line from the only surviving blastomere of a four-cell stage embryo. From Wordnik.com. [PLoS ONE Alerts: New Articles] Reference
As a result, ABarp, instead of ABara, contacts the MS blastomere in the12-cell-stage embryos. From Wordnik.com. [PLoS Biology: New Articles] Reference
A single blastomere of a four-cell stage human embryo could therefore also form a teratocarcinoma. From Wordnik.com. [PLoS ONE Alerts: New Articles] Reference
In fact, the blastomere extraction technique is commonly used in pre-implantation genetic diagnosis. From Wordnik.com. [latimes.com - News] Reference
More information: Chiral blastomere arrangement dictates zygotic left-right asymmetry pathway in snails. From Wordnik.com. [PhysOrg.com - latest science and technology news stories] Reference
Which developmental stage of foetal growth defines your threshold for transition from blastomere to human?. From Wordnik.com. [Army Rumour Service] Reference
The findings support the use of ACT's single blastomere-derived human embryonic stem cell lines which do not display early aging. From Wordnik.com. [THE MEDICAL NEWS] Reference
XWnt8 +/− 250 pg NKD1 (wild-type or mutant) with 200 pg EGFP (lineage tracer) mRNAs into one ventral blastomere at the 4-cell stage. From Wordnik.com. [PLoS ONE Alerts: New Articles] Reference
In animal tests, the blastomere-derived retinal cells grew well and allowed the light-detecting rod and cone cells to regenerate, improving the animals 'vision. From Wordnik.com. [NYT > Home Page]
"This study further supports our single blastomere-derived human embryonic stem cell technology platform," stated William M. Caldwell, CEO and Chairman of ACTC. From Wordnik.com. [THE MEDICAL NEWS] Reference
The stem cell line was created from a single blastomere cell that was extracted from an eight-cell embryo using a technique that does not require the destruction of an embryo. From Wordnik.com. [latimes.com - News] Reference
For single-blastomere injections, embryos were cultured in ASW until 40 min after the first cell division and rinsed four times with ice-cold calcium-magnesium-free sea water (CMFSW). From Wordnik.com. [PLoS Biology: New Articles] Reference
It is thus tempting to speculate that the blastomere that gave rise to CH-ES1 may have been tetraploid and that subsequent chromosomal loss resulted in an EC-like phenotype by a mechanism comparable to that by which EC cells arise. From Wordnik.com. [PLoS ONE Alerts: New Articles] Reference
In conclusion, the first teratocarcinoma-like hESC line derived from a single blastomere showed many features typical of malignant cells, such as trisomies, duplications, deletions, and increased copy numbers of oncogenes, explaining its malignancy. From Wordnik.com. [PLoS ONE Alerts: New Articles] Reference
In order to test embryos thought to be at risk for serious genetic defects, PGD removes a single cell, or blastomere, from a couple’s embryo and examines it in a lab for irregularities. From Wordnik.com. [Scientific Sidestep?] Reference
In practice, Lanza’s technique would take a blastomere from an embryo donated for PGD, allow it to divide, and use the new cells to create stem-cell lines while sending one of the cells off for genetic diagnosis. From Wordnik.com. [Scientific Sidestep?] Reference
ACT’s blastomere program was cited by the NIH as an alternative method in its implementation plan; therefore, should the company’s blastomere technique satisfy NIH qualifications, ACT could qualify for federal funding from the NIH. From Wordnik.com. [Barbara Walters' Television Special Highlights Role Advanced Cell Technology's Embryonic Stem Cells Breakthroughs] Reference
Pmar1′s ability to activate the PMC-GRN in any blastomere provides a unique opportunity to understand how signaling outputs of the PMC-GRN are interpreted through the regulatory logic of the recipient E-EM / En GRN (. From Wordnik.com. [PLoS Biology: New Articles] Reference
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