The active principle is a chemical called ouabain, and it is a powerful stimulant of the muscles of the heart. From Wordnik.com. [The Serpent and the Rainbow] Reference
Myers, Widespread occurrence in frogs and toads of skin compounds interacting with the ouabain site of Na+, K+, ATPase, Science 208 1980: 503-5; Kennedy, A. From Wordnik.com. [The Serpent and the Rainbow] Reference
Ph.D. thesis research on the effects of experimental congestive heart failure, asphyxia and ouabain on high energy phosphates and creatine content of the guinea pig heart. From Wordnik.com. [Robert F. Furchgott - Autobiography] Reference
Action of ouabain on submaxillary secretion in the dog. From Wordnik.com. [xml's Blinklist.com] Reference
Figure 5C, the application of 0.1 mM ouabain for 1 min substantially reduces the massive postplateau hyperpolarizations in membrane-tethered δ-ACTX-Hv1a-expressing lLN. From Wordnik.com. [PLoS Biology: New Articles] Reference
"It's been known for a long time that injecting the sodium/potassium pump inhibitor ouabain into the brain can induce seizures in rats," says Clapcote, and it's also known that mice lacking two of three forms of the pump - either the "alpha1" or "alpha2" forms - are free from seizures. From Wordnik.com. [New Scientist - Online News] Reference
ouabain, 113. From Wordnik.com. [The Serpent and the Rainbow] Reference
Sixth, if it is a drug and is not designated solely by a name recognized in an official compendium, unless its label bears (1) the common or usual name of the drug, if such there be; and (2) in case it is fabricated from two or more ingredients, the common or usual name of each active in - gredient, including the kind and quantity or proportion of any alcohol, and also including whether active or not, the name and quantity or proportion of any bromides, ether, chloroform, acetanilid, acetophenetidin, amidopyrine, anti - pyrine, atropine, hyoscine, hyoscyamine, arsenic, digitalis, digitalis glucosides, mercury, ouabain, strophanthin, strych - nine, thyroid or any derivative or preparation of any such substances, contained therein; provided, that to the extent that compliance with the requirements of clause (2) of this paragraph is impracticable, exemptions may be established by regulations promulgated by the department of pubUc Acts, 1948. —. From Wordnik.com. [Acts and resolves passed by the General Court] Reference
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