Other common autosomal recessive diseases such as sickle cell anemia have been found to protect carriers from other diseases, a concept known as heterozygote advantage. From Wordnik.com. ["Sicker than a Doorknob"] Reference
This is known as heterozygote advantage. From Wordnik.com. [Archive 2005-05-01] Reference
A1A2 heterozygote is phenotypically identical to the. From Wordnik.com. [Population Genetics] Reference
This is where the heterozygote has a higher fitness than either homozygote. From Wordnik.com. [Red Lynx Simulator - The Panda's Thumb] Reference
A1A2 heterozygote produces gametes bearing the A1 and A2 alleles in equal proportion. From Wordnik.com. [Population Genetics] Reference
A1A1 homozygote is fitter than the A1A2 heterozygote, which in turn is fitter than the. From Wordnik.com. [Population Genetics] Reference
Lande 1979 looked at the problem of fixation for chromosomal rearrangements with heterozygote disadvantage. From Wordnik.com. [The Panda's Thumb: Arthur Hunt Archives] Reference
But if two dominant, or two recessive, alleles occur together in a heterozygote, interesting things can happen. From Wordnik.com. [The Rise of Human Chromosome 2: Beyond the Deme - The Panda's Thumb] Reference
The example is of heterozygote superiority, though any example where the allelic effects on phenotype are non-additive would do. From Wordnik.com. [Miss Winter Solstice] Reference
Ford also showed that the selective advantage for the rarer of the genes varied widely, from -0.10 to +0.20, and that there was no evidence of heterozygote advantage. From Wordnik.com. [Evolutionary Genetics] Reference
He had also M694V / E148Q compound heterozygote mutation. From Wordnik.com. [BioMed Central - Latest articles] Reference
We are only interested in the double heterozygote (+/d; u/+). From Wordnik.com. [OpenWetWare - Recent changes [en]] Reference
A heterozygote frameshift mutation, c. 390delG, was detected in. From Wordnik.com. [New England Journal of Medicine] Reference
All molecules of protein X in the heterozygote strain are GFP tagged. From Wordnik.com. [Naturejobs - All Jobs] Reference
The heterozygote individual in typical cases shows the dominant character. From Wordnik.com. [Hormones and Heredity] Reference
There are some theoretical reasons to be skeptical of pervasive heterozygote advantage. From Wordnik.com. [ScienceBlogs Channel : Life Science] Reference
It would seem, therefore, that the pile is the heterozygote of black-red and 'dominant' white. From Wordnik.com. [Hormones and Heredity] Reference
SFT (sft-4537, right; Online Methods) and a highly heterotic sft-4537/+ heterozygote (middle). From Wordnik.com. [Naturejobs - All Jobs] Reference
If a heterozygote is bred with a pure recessive the offspring are half heterozygote and half recessive. From Wordnik.com. [Hormones and Heredity] Reference
An individual may be a homozygote with respect to one factor and a heterozygote with respect to another. From Wordnik.com. [Applied Eugenics] Reference
(C) Southern analysis of genomic DNA isolated from representative pups. + / +, wild type; + / −, heterozygote. From Wordnik.com. [PLoS ONE Alerts: New Articles] Reference
It is possible that the father is a heterozygote, carrying one variant for light skin, and one variant for dark skin. From Wordnik.com. [ScienceBlogs Channel : Life Science] Reference
Facial flushing in a 22-year-old ALDH2 heterozygote (single-copy carrier) before (left) and after (right) drinking alcohol. From Wordnik.com. [Livescience.com] Reference
The heterozygote excess and the lack of inbreeding could be interpreted as a hitherto unknown outcrossing strategy of the species. From Wordnik.com. [BioMed Central - Latest articles] Reference
Any gene for which your parent was a heterozygote, you have a 50\% chance of being a homozygote (for one of the two possible alleles). From Wordnik.com. [The Globe and Mail - Home RSS feed] Reference
Since the mother is European, the potential combinations on this locus would be heterozygote, or homozygote for the light skin variant. From Wordnik.com. [ScienceBlogs Channel : Life Science] Reference
D was set equal to zero if the heterozygote differed less than 5% from the mean of the homozygotic values. From Wordnik.com. [PLoS ONE Alerts: New Articles] Reference
If the heterozygote has a genotypic value less than or greater than both homozygotes (. From Wordnik.com. [PLoS ONE Alerts: New Articles] Reference
In heterozygote animals. From Wordnik.com. [BioMed Central - Latest articles] Reference
2, σ2) corresponding to the heterozygote were initially set to zero, implying that only the homozygote SL/SL is susceptible to scrapie. From Wordnik.com. [PLoS ONE Alerts: New Articles] Reference
I, myself, am a heterozygote. From Wordnik.com. [When The Bough Breaks]
445 heterozygote high-confidence SNPs. From Wordnik.com. [Naturejobs - All Jobs] Reference
Wild-type-WT, heterozygote-HET, knockout-KO. From Wordnik.com. [PLoS ONE Alerts: New Articles] Reference
) actually decrease expression by 23 % in the heterozygote (30-70% FDR). From Wordnik.com. [Naturejobs - All Jobs] Reference
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