We did not assume mutations to be either lethal or pleiotropic. From Wordnik.com. [Critique of Behe and Snoke Available - The Panda's Thumb] Reference
Reproductive isolation as a pleiotropic effect of copper tolerance in Mimulus guttatus. From Wordnik.com. [Yet another controversy - the Intelligent Deceiver - The Panda's Thumb] Reference
This may be an important pleiotropic effect whereby rosuvastatin reduces mortality in patients with coronary artery disease. From Wordnik.com. [The adherer effect | The Blog of Michael R. Eades, M.D.] Reference
Molecular mechanisms underlying the pleiotropic nature of SO are only partly understood. From Wordnik.com. [PLoS ONE Alerts: New Articles] Reference
Likewise, mouse genetic models of disease often have pleiotropic and overlapping phenotypes. From Wordnik.com. [BioMed Central - Latest articles] Reference
Unlike other mutants defective in RdDM, dms4 mutants have a pleiotropic developmental phenotype. From Wordnik.com. [Naturejobs - All Jobs] Reference
This suggests pleiotropic effects of TaVRN2 in wheat development and adaptability to the environment. From Wordnik.com. [PLoS ONE Alerts: New Articles] Reference
Wortham B, Oliveira M, Patel C (2007) Polyamines in bacteria: pleiotropic effects yet specific mechanisms. From Wordnik.com. [PLoS ONE Alerts: New Articles] Reference
As one approach to this problem, we have used alleles of a pleiotropic regulator of secondary metabolism from. From Wordnik.com. [Naturejobs - All Jobs] Reference
Aminoglycoside-class antibiotics bind directly to ribosomal RNA, imparting pleiotropic effects on ribosome function. From Wordnik.com. [Naturejobs - All Jobs] Reference
Gluckman PD, Feldman EL, Werther GA (2005) The insulin-like growth factor system and its pleiotropic functions in brain. From Wordnik.com. [PLoS ONE Alerts: New Articles] Reference
Understanding the pleiotropic effects of FTi regulators, and how they account for yield components and stress tolerance. From Wordnik.com. [Aktuellste Pressemeldungen der PresseBox] Reference
Allelic effects of three fat traits from the same gamete were highly correlated suggesting the presence of a pleiotropic QTL. From Wordnik.com. [BioMed Central - Latest articles] Reference
Vitamin D has a number of pleiotropic effects in a variety of tissues, in addition to its well-known effects on mineral metabolism. From Wordnik.com. [Naturejobs - All Jobs] Reference
Statins reduce risk of cardiovascular events and have beneficial pleiotropic effects; both may reduce mortality in critically ill patients. From Wordnik.com. [BioMed Central - Latest articles] Reference
Interleukin (IL) -18 is a cytokine originally discovered as an important modulator of immune responses and subsequently shown to be pleiotropic. From Wordnik.com. [BioMed Central - Latest articles] Reference
This argument rests on two claims: (1) the modular nature of cis-regulatory elements largely frees them from deleterious pleiotropic effects, and. From Wordnik.com. [Evolution News & Views] Reference
Along with the fluctuating dominance in fitness at the Eda locus, these results indicate that there may be additional pleiotropic effects of this gene. From Wordnik.com. [ScienceBlogs Channel : Life Science] Reference
Here, we show that, lactoferrin (LTF), a pleiotropic 80-kDa glycoprotein with iron-binding properties, acts as a powerful inhibitor of eosinophil migration. From Wordnik.com. [Naturejobs - All Jobs] Reference
Drought-tolerant Arabidopsis thaliana were engineered through overexpression of the transcription factor ABF3 in order to investigate unintended pleiotropic effects. From Wordnik.com. [BioMed Central - Latest articles] Reference
This is consistent with the pleiotropic effects observed in numerous studies, such as those involving global inhibition of miRNA production by ablation of the Dicer gene. From Wordnik.com. [PLoS ONE Alerts: New Articles] Reference
However, these events are relatively rare and may have accompanying deleterious pleiotropic effects, thereby limiting their contribution to evolution under natural selection. From Wordnik.com. [Citizendium, the Citizens' Compendium - Recent changes [en]] Reference
1996 “Loss of fibrinogen rescues mice from the pleiotropic effects of plasminogen deficiency.”. From Wordnik.com. [Robert Camp:Can Intelligent Design be considered scientific in the same way that SETI is? - The Panda's Thumb] Reference
7. In the Discussion, Lynch writes that we assume mutations have “lethal pleiotropic effects.”. From Wordnik.com. [Critique of Behe and Snoke Available - The Panda's Thumb] Reference
"Mortality reduction with influenza vaccine in patients with pneumonia outside" flu "season: pleiotropic benefits or residual confounding?. From Wordnik.com. [Crooks and Liars] Reference
These are known as "pleiotropic" and as "polygenic" effects, respectively. From Wordnik.com. [Making a Monkey out of Pat Buchanan] Reference
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