· Single puncture, perpendicular to the abdomen, on a line joining the umbilicus and the anterior superior iliac spine, usually on the left, to avoid perforation of the cecum; on the right in the case of massive splenomegaly.    From Wordnik.com.  [Chapter 5] Reference

Examination reveals a heart murmur and splenomegaly.    From Wordnik.com.  [Recently Uploaded Slideshows] Reference

Of the 53 evaluable subjects who had splenomegaly at baseline.    From Wordnik.com. Reference

We, therefore, keep age, baseline WBC, T-cell immunophenotype and splenomegaly in the final model.    From Wordnik.com.  [BioMed Central - Latest articles] Reference

After follow-up for at least a year, 48% of 155 patients had greater than a 50% reduction in splenomegaly.    From Wordnik.com.  [MedPageToday.com - medical news plus CME for physicians] Reference

Enlargement of liver (also known as hepatomegaly), enlargement of spleen (known as splenomegaly) in some cases.    From Wordnik.com. Reference

The disease may first be noticed in childhood or in early adult life, when the anemia and splenomegaly are noted.    From Wordnik.com.  [Citizendium, the Citizens' Compendium - Recent changes [en]] Reference

InPlay: YM BioSciences reports significant response rates in anemia, splenomegaly, and constitutional symptoms in CYT387 Trial.    From Wordnik.com.  [Ym Biosciences Reports Significant Response Rates in Anemia, Splenomegaly, and Constitutional Symptoms From the Phase I/II Trial of its Jak1/Jak2 Inhibitor, Cyt387, in Myelofibrosis - Yahoo! Finance] Reference

The decoction of Bhumyamlaki augments the function of the liver gland and it can be used as a blood purifier in hepato-splenomegaly.    From Wordnik.com.  [xml's Blinklist.com] Reference

Group of children at low risk of TLS can, therefore, be defined as absence of age, baseline WBC, splenomegaly and T-cell immunophenotype.    From Wordnik.com.  [BioMed Central - Latest articles] Reference

No, it's not a given that you'd develop splenomegaly but it IS the main complication that occurs in about half the people who get mono.    From Wordnik.com.  [Yahoo! Answers: Latest Questions] Reference

With optimized dosing, reduction in splenomegaly was evident as early as one month, and early improvement has been maintained for as long as two years.    From Wordnik.com.  [MedPageToday.com - medical news plus CME for physicians] Reference

When REP 9C (which lacks CpG motifs) was compared to REP 9, it exhibited comparable antiviral activity as REP 9 but was not associated with splenomegaly.    From Wordnik.com.  [BioMed Central - Latest articles] Reference

The principal benefit is a rapid and significant reduction in splenomegaly, accompanied by equally rapid and substantial improvement in symptoms, he added.    From Wordnik.com.  [MedPageToday.com - medical news plus CME for physicians] Reference

We describe the first case of CHF presenting in an otherwise healthy child, with thrombocytopenia and splenomegaly as the only manifestations of the disease.    From Wordnik.com.  [BioMed Central - Latest articles] Reference

Other notable findings at admission were splenomegaly, pancytopenia, hyponatremia, elevated levels of liver enzymes, hyperferritinemia and hypofibrinogenemia.    From Wordnik.com.  [Naturejobs - All Jobs] Reference

(A) Representative images of spleen and lymph node of control (Ctrl) and N1N2K5 mice showing splenomegaly and lymphadenopathy (n = 12, three individual experiments).    From Wordnik.com.  [PLoS ONE Alerts: New Articles] Reference

Moreover, the original model consisting of age, baseline WBC, mediastinal mass and splenomegaly, was not validated although some goodness of fit properties were reported.    From Wordnik.com.  [BioMed Central - Latest articles] Reference

For instance, splenomegaly is the 3rd important variable using bootstrapping, however, it is the 5 th selected variable in the training set using the random split strategy.    From Wordnik.com.  [BioMed Central - Latest articles] Reference

Untreated, this results in death before age twenty: treatment consists of periodic blood transfusion; splenectomy if splenomegaly is present, and treatment of transfusion-caused iron overload.    From Wordnik.com.  [Citizendium, the Citizens' Compendium - Recent changes [en]] Reference

Two male patients with splenomegaly carried the FIP1L1-PDGFRA rearrangement, whilst 2 others were ultimately classified as suffering from idiopathic hypereosinophlic syndrome (HES) and one from systemic mastocytosis.    From Wordnik.com.  [BioMed Central - Latest articles] Reference

Preliminary data reported at the 2008 ASH meeting suggested INCB018424 reduced splenomegaly and symptoms associated with myelofibrosis, and Verstovsek presented results from analysis of more mature data from that same trial.    From Wordnik.com.  [MedPageToday.com - medical news plus CME for physicians] Reference

Nevertheless heavy physical activity and contact sports should be avoided to mitigate the risk of splenic rupture, for at least one month following initial infection and until splenomegaly has resolved, as determined by ultrasound scan.    From Wordnik.com. Reference

Patients were eligible to participate in the study if they presented with disease-related anemia and had at least one of the following clinical manifestations of Gaucher disease: thrombocytopenia, moderate splenomegaly or a readily palpable enlarged liver.    From Wordnik.com.  [RedOrbit News - Technology] Reference

MPNs are a related group of hematological neoplasms characterized by dysfunction of the bone marrow resulting in either over production of blood cells or ineffective hematopoiesis leading to production of blood cells in the spleen and resulting in massive splenomegaly.    From Wordnik.com. Reference

N1N2K5 and RBP-JK5 mice developed splenomegaly, as well as lymphadenopathy (.    From Wordnik.com.  [PLoS ONE Alerts: New Articles] Reference

Upon dissection, we observed modest splenomegaly in hIL-7 expressing mice compared to controls (.    From Wordnik.com.  [PLoS ONE Alerts: New Articles] Reference

Spleen Size Reduction: Twenty nine (97%) of the 30 evaluable subjects who had splenomegaly at baseline (median 20 cm; range 10-32 cm) had some degree of spleen size reduction (median 9.    From Wordnik.com.  [Ym Biosciences Reports Significant Response Rates in Anemia, Splenomegaly, and Constitutional Symptoms From the Phase I/II Trial of its Jak1/Jak2 Inhibitor, Cyt387, in Myelofibrosis - Yahoo! Finance] Reference

Strikingly, the size as well as the histology of spleens derived from RBP-JK5/G-CSF +/− mice was comparable to control animals, while RBP-JK5 mice showed clear splenomegaly with loss of the white and red pulp (.    From Wordnik.com.  [PLoS ONE Alerts: New Articles] Reference

Figure S1) were found in the serum, nor did the mice develop splenomegaly, lymphoproliferative disease, or signs of chronic inflammation-all aspects of autoimmunity normally controlled by T reg cells. king, a Mutation in Carma1.    From Wordnik.com.  [PLoS Biology: New Articles] Reference

Hepatomegaly and splenomegaly. e.    From Wordnik.com.  [Recently Uploaded Slideshows] Reference

Diseases associated with splenomegaly.    From Wordnik.com.  [conditions we treat] Reference

Complications:  Congestive splenomegaly.    From Wordnik.com.  [Recently Uploaded Slideshows] Reference

74-year-old Greek woman with splenomegaly.    From Wordnik.com.  [PLoS ONE Alerts: New Articles] Reference

Many patients develop severe anemia, weakness, fatigue, splenomegaly, and hepatomegaly.    From Wordnik.com.  [MedPageToday.com - medical news plus CME for physicians] Reference

Prolonged fever, splenomegaly, bicytopenia, hypofibrinogenemia, hyperferritinemia and hypertriglyceridemia confirmed HFS diagnosis.    From Wordnik.com.  [BioMed Central - Latest articles] Reference