Using their technique, the research team have shown that a particular subset of the pancreatic cells, the so-called acinar cells, are indeed stem cells.    From Wordnik.com.  [Zee News : India National] Reference

As Bensley and others have shown there may still remain, at this period after duct-ligation, a considerable amount of more or less normal acinar tissue.    From Wordnik.com.  [John Macleod - Nobel Lecture] Reference

The vertebrate pancreas contains islet, acinar and ductal cells.    From Wordnik.com.  [BioMed Central - Latest articles] Reference

This effect was more profound in acinar cells prepared from InsP.    From Wordnik.com.  [Journal of Biological Chemistry current issue] Reference

Interestingly, beneficial results were seen in intra-acinar inflammation.    From Wordnik.com.  [PhysOrg.com - latest science and technology news stories] Reference

IICR was measured in permeabilized acinar cells from wild-type (WT) and InsP3.    From Wordnik.com.  [Journal of Biological Chemistry current issue] Reference

The new way CTRC mutants are attacking acinar cells may not be unique, either.    From Wordnik.com.  [PhysOrg.com - latest science and technology news stories] Reference

They also showed that beta catenin was required for efficient acinar regeneration.    From Wordnik.com.  [Medlogs - Recent stories] Reference

"These results indicate that beta-catenin is essential for acinar regeneration," says Hebrok.    From Wordnik.com.  [Medlogs - Recent stories] Reference

In this new study, they show that the misfolding of mutant digestive enzymes also kills acinar cells.    From Wordnik.com.  [PhysOrg.com - latest science and technology news stories] Reference

"Thus, different mechanisms converge onto a common endpoint, acinar cell death," says Dr. Sahin-Toth.    From Wordnik.com.  [PhysOrg.com - latest science and technology news stories] Reference

In acute and chronic pancreatitis, acinar cells of the pancreas are persistently inflamed and injured.    From Wordnik.com.  [Medlogs - Recent stories] Reference

In the normal mice, the acinar cells transiently induced embryonic signaling and regenerated as expected.    From Wordnik.com.  [Medlogs - Recent stories] Reference

(InsP3R) is the primary signal driving digestive enzyme and fluid secretion from pancreatic acinar cells.    From Wordnik.com.  [Journal of Biological Chemistry current issue] Reference

Induction of MLK3 expression dramatically increases acinar size and modestly perturbs apicobasal polarity.    From Wordnik.com.  [Naturejobs - All Jobs] Reference

The scientists tracked the behavior, or "fate," of the fluorescently labeled acinar cells in both sets of mice.    From Wordnik.com.  [Medlogs - Recent stories] Reference

The GSDM researchers are the first to show that a mutant digestive enzyme can harm acinar cells through ER stress.    From Wordnik.com.  [PhysOrg.com - latest science and technology news stories] Reference

However, the findings have been puzzling, because expression of mutated Kras does not guarantee acinar reprogramming.    From Wordnik.com.  [Medlogs - Recent stories] Reference

Here is a small selection of such papers: Fine structural analysis of pancreatic acinar cell nuclei from mice fed on GM soybean.    From Wordnik.com.  [Libertarian Blog Place] Reference

Prostatic specific antigen (PSA) PSA is a 34KD glycoprotein enzyme produced by the columnar acinar and ductal prostatic epithelial cells.    From Wordnik.com.  [xml's Blinklist.com] Reference

Subsequently, scientists in other labs have confirmed that mutated Kras can initiate the development of precursors to PDA in acinar cells.    From Wordnik.com.  [Medlogs - Recent stories] Reference

When mutant Kras is active in the acinar cells of mice with chemically-induced acute pancreatitis, the development of precursors of PDA progression is accelerated.    From Wordnik.com.  [Medlogs - Recent stories] Reference

They showed in a Journal of Biological Chemistry paper that the activity of mutant digestive enzymes damages acinar cells-those that make and give out digestive enzymes.    From Wordnik.com.  [PhysOrg.com - latest science and technology news stories] Reference

(vol. 120, issue 2, 2010), the team set out to investigate how mutant Kras co-opts the damaged acinar cells.    From Wordnik.com.  [Medlogs - Recent stories] Reference

3R are the predominant isoforms expressed in acinar cells and are required for proper exocrine gland function.    From Wordnik.com.  [Journal of Biological Chemistry current issue] Reference

Round structures generally developed a robust basal lamina (BL), encapsulating both spheroids and acinar structures (.    From Wordnik.com.  [PLoS ONE Alerts: New Articles] Reference

"Pancreatic acinar cancers represent about 1% of pancreatic cancer cases in US, which translates to about 400-500 new cases per year.    From Wordnik.com.  [Minyanville] Reference

50 was 10-fold higher in acinar cells isolated from InsP.    From Wordnik.com.  [Journal of Biological Chemistry current issue] Reference

3-induced Ca2+ release (IICR) to ATP in pancreatic acinar cells.    From Wordnik.com.  [Journal of Biological Chemistry current issue] Reference

Ca2+ signaling in WT pancreatic acinar cells.    From Wordnik.com.  [Journal of Biological Chemistry current issue] Reference