He has isolated, together with his students and associates, a number of new antibiotics, including actinomycin (1940), clavacin, streptothricin (1942), streptomycin (1943), grisein. From Wordnik.com. [Selman A. Waksman - Biography] Reference
Action actinomycin D auxin-induced growth Avena coleoptile section. From Wordnik.com. [xml's Blinklist.com] Reference
After 2 d, actinomycin D (act D, 1 μg ml − 1) or vehicle was added to the medium. From Wordnik.com. [Naturejobs - All Jobs] Reference
Kelley DE (1970) Inhibition of RNA synthesis by actinomycin D: characteristic dose-response of different RNA species. From Wordnik.com. [PLoS ONE Alerts: New Articles] Reference
Cells were harvested at the indicated time points (hours after addition of actinomycin or vehicle or transfection with agRNA). From Wordnik.com. [Naturejobs - All Jobs] Reference
(Pol I) are polyadenylated and accumulate markedly after treatment with low concentrations of actinomycin D (ActD), which blocks the synthesis of full-length rRNA. From Wordnik.com. [Naturejobs - All Jobs] Reference
Conversely, Lin and colleagues reported that memory extinction is insensitive to actinomycin-D and depends upon calcineurin activity that induces dephosphorylation of cAMP response element binding protein. From Wordnik.com. [PLoS ONE Alerts: New Articles] Reference
Interference with ribosomal biogenesis by actinomycin D further increased the level of apoptosis in L11-deficient embryos (data not shown), as ribosomal biogenesis was already compromised in these embryos. From Wordnik.com. [PLoS ONE Alerts: New Articles] Reference
To measure cellular apoptotic signaling, transfected T cells were harvested, washed twice with PBS, and reacted with PE-conjugated anti-annexin V and 7-amino-actinomycin D (7AAD) according to the manufacturer's directions (BD Pharmingen). From Wordnik.com. [PLoS ONE Alerts: New Articles] Reference
Stalling of Pol II, caused by DNA damage, a DNA intercalating agent (actinomycin D) or microinjection of anti-Pol II antibodies in the nuclei, leads to p53 induction in a manner that depends on ATR and the single stranded DNA binding protein RPA. From Wordnik.com. [PLoS ONE Alerts: New Articles] Reference
In human embryonic kidney-293 cells heterologously expressing the full-length 3'-UTR-P2X7 luciferase reporter, miR-186 and miR-150 inhibitors increased luciferase activity, whereas miR-186 and miR-150 mimics decreased luciferase activity after actinomycin D treatment. From Wordnik.com. [Journal of Biological Chemistry current issue] Reference
Solid circle represents the value of real time PCR with the samples from Caco2-BBE cells without treatment, open circle represents the value of real time PCR with the samples from Caco2-BBE treated with actinomycin D, solid triangle represents real time PCR with the samples from Caco2-BBE treated with actinomycin D and hyperosmolarity. From Wordnik.com. [PLoS ONE Alerts: New Articles] Reference
In MCF7 cells, the E2-stimulated expression of PCNA was blocked by co-treatment with ICI 182,170 and by inhibition of gene transcription using actinomycin D (ActD) (. From Wordnik.com. [PLoS ONE Alerts: New Articles] Reference
«actinomycin» and it was very toxic. From Wordnik.com. [Nobel Prize in Physiology or Medicine 1952 - Presentation Speech] Reference
Where indicated, treatments included vehicle control (100\% EtOH), estradiol (10 nM or 100 nM, Sigma), actinomycin D (ActD, 2 µg / mL, Sigma), cycloheximide (CHX, 25 µg / mL, Sigma), and ICI 182,780 (1 µM, Tocris Biosciences). From Wordnik.com. [PLoS ONE Alerts: New Articles] Reference
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