With all this focus on polyketide/macrolide synthesis, I thought I’d highlight an interesting review in this week’s Angewandte; a genuine masterclass in the aldol reaction.    From Wordnik.com.  [Rambles at starchamber.com » Blog Archive » For the love of chemical synthesis] Reference

In fact, our studies show that serine meets the first two criteria, and recent work24 has demonstrated that serine catalyses certain asymmetric aldol reactions with high enantioselectivity; it has also been highlighted as one of a small number of amino acids likely to have played an important role in prebiotic chemistry25, 26.    From Wordnik.com.  [Chirality of life: Another false positive? - The Panda's Thumb] Reference

The implementation of the aldol reaction in the active site of an enzyme has been an important challenge.    From Wordnik.com.  [Biosingularity] Reference

Ketones can be used in aldol condensation reactions, although they are less reactive than aldehydes in this regard.    From Wordnik.com.  [Citizendium, the Citizens' Compendium - Recent changes [en]] Reference

Coalesced work from home online jobs, red kindliness, red granger and mastoidal aldol, but postnatal pylon say protactinium to pelvimetry the satiety are reputably way.    From Wordnik.com.  [POWET.TV] Reference

In a previous paper, published in the journal Science on March 7, the chemists reported another successful chemical reaction that uses designer enzymes to catalyze a retro-aldol reaction, which involves breaking a carbon-carbon bond.    From Wordnik.com.  [Biosingularity] Reference

Last night I was even at the stage of sitting in the exam hall waiting to be told to open the test paper, when I realised that I could recall not one of the countless details of reagents, methods and strategies involved in the Grignard reaction in particular (yes, alkylmagnesium, I know that much) or the aldol reaction, Claesen rerrangement, Friedel-Crafts acylation and all the rest.    From Wordnik.com.  [homunculus] Reference

2BOTf anti-selective aldol condensation according to a known procedure.    From Wordnik.com.  [Naturejobs - All Jobs] Reference

20, followed by chiral auxiliary cleavage and subsequent β-lactonization (syn-selective aldol condensations according to a known procedure.    From Wordnik.com.  [Naturejobs - All Jobs] Reference