The propargyl (alkyne) and azido groups are bioorthogonal reaction partners.    From Wordnik.com.  [PLoS ONE Alerts: New Articles] Reference

List of top 100 targets identified by LC-MS/MS using 4-PPB, the alkyne click derivative of.    From Wordnik.com.  [PLoS ONE Alerts: New Articles] Reference

Thus, an alkyne-modified protein can be tagged using an azide-conjugated biotin or, vice versa, an azide-modified protein can react with an alkyne-derivatized biotin.    From Wordnik.com.  [PLoS ONE Alerts: New Articles] Reference

The supernatants were then treated with the alkyne - or azide-conjugated biotin-tags, and click chemistry was used to label the targets of the 4-BPB click derivatives.    From Wordnik.com.  [PLoS ONE Alerts: New Articles] Reference

The alkyne group on the added peptide can potentially chemically react with the azide group of the library's peptides, to create a new peptide that is now two segments long.    From Wordnik.com.  [Health News from Medical News Today] Reference

That first peptide - which is about a third of the length of the final capture agent the scientists are trying to make - is then isolated, purified, and modified on one end by the addition of a chemical group called an alkyne.    From Wordnik.com.  [Health News from Medical News Today] Reference

Click chemistry is best known for a copper-catalyzed azide-alkyne reaction that makes it possible for certain chemical building blocks to "click" together in an irreversible linkage, analagous to the snapping together of Lego blocks.    From Wordnik.com.  [THE MEDICAL NEWS] Reference

The two-segment-long peptide then is isolated and purified, "and then we modify the end of that with an alkyne and add it back to the library to produce a three-segment peptide, which is long enough to be both selective for and specific to the target protein," Dr. Heath said.    From Wordnik.com.  [PhysOrg.com - latest science and technology news stories] Reference

Since its introduction in 2001 by the Nobel laureate chemist Barry Sharpless of the Scripps Research Institute, the copper-catalyzed azide-alkyne reaction has proven extremely valuable for attaching small molecular probes to various biomolecules in a test tube or on fixed cells.    From Wordnik.com.  [THE MEDICAL NEWS] Reference

Follow the leader: the use of leader peptides to guide natural product biosynthesis Rapid behavior-based identification of neuroactive small molecules in the zebrafish Capture and release of alkyne-derivatized glycerophospholipids using cobalt chemistry Domino access to highly substituted chromans and isochromans from carbohydrates.    From Wordnik.com.  [Naturejobs - All Jobs] Reference

Slide 3: Unsaturated Hydrocarbons Unsaturated hydrocarbon: contains one or more x carbon-carbon double or triple bonds Alkene: contains a carbon-carbon double bond x and has the general formula CnH2n H H C C H H Ethylene (an alkene) alkyne: H­C C­H a carbon-carbon triple bond and contains x has the general formula CnH2n-2 Acetylene (an alkyne).    From Wordnik.com.  [Recently Uploaded Slideshows] Reference

50 µM of the alkyne - or azide-conjugated biotin-tags (50X stock in DMSO), 1 mM tris.    From Wordnik.com.  [PLoS ONE Alerts: New Articles] Reference

6. (b) An Ugi four-component condensation reaction followed by Huisgen cycloaddition of an azide and an alkyne.    From Wordnik.com.  [Naturejobs - All Jobs] Reference