In fact, their eyes were somehat larger than would be expected from allometric dropoff in eye size in tetrapods. From Wordnik.com. [Big Bird] Reference
Professor D'Arcy Wentworth Thompson, last of the great Victorian polymaths, author inter alia of the classic allometric study On. From Wordnik.com. [Sir James W. Black - Autobiography] Reference
How in the world can someone understand a paper describing the allometric law relating metabolic rate to body mass unless they understand power law relations, exponential and logarithmic functions, and linear regression?. From Wordnik.com. [How would *you* strengthen science in the U.S.? - The Panda's Thumb] Reference
Substituting into the allometric for - drug dependent. From Wordnik.com. [Recently Uploaded Slideshows] Reference
West GB, Brown JH, Enquist BJ (1999) The fourth dimension of life: Fractal geometry and allometric scaling of organisms. From Wordnik.com. [PLoS ONE Alerts: New Articles] Reference
Extended neoteny and late stage allometric growth increase morphological disparity between growth stages in at least some dinosaurs. From Wordnik.com. [PLoS ONE Alerts: New Articles] Reference
The first principal component correlated positively with centroid-size, but within-species allometric relationships differed markedly. From Wordnik.com. [BioMed Central - Latest articles] Reference
This result is supported by variation among structures on the strength of their loadings on the principal size axis of the allometric analysis. From Wordnik.com. [BioMed Central - Latest articles] Reference
These lambeosaurine taxa experienced cranial allometric growth and retained juvenile characters (neoteny) until the skulls reached approximately 50% adult size. From Wordnik.com. [PLoS ONE Alerts: New Articles] Reference
The values estimated by allometric scaling were The formula for predicting the plasma half-life compared with those observed in the single-dose was: human volunteer study (Table 8.5). From Wordnik.com. [Recently Uploaded Slideshows] Reference
Model Quantum metabolism is an analytic theory of metabolic regulation which exploits the methodology of quantum mechanics to derive allometric rules relating cellular metabolic rate and cell size. From Wordnik.com. [BioMed Central - Latest articles] Reference
Renal clearance is subject to an allometric compound X, our scaling tactics did eventually relationship and can generally be scaled across teach us about a new clearance mechanism, and species (see below). From Wordnik.com. [Recently Uploaded Slideshows] Reference
When used in conjunction with the Simcyp Population-based ADME Simulator, Simcyp Rat allows comparison of human and animal data without relying on allometric scaling which may not be a valid approach for some parameters. From Wordnik.com. [Medlogs - Recent stories] Reference
The allometric equa - tion is Y ¼ aW b, and a log transformation of this allometric approaches to drug discovery formula yields the straight line: Using limited data, allometric scaling may be use - log Y ¼ b log W þ log a; ful in drug discovery. From Wordnik.com. [Recently Uploaded Slideshows] Reference
We estimated complexity in two ways, measuring dissimilarity within timescales by calculating entropy after a symbolic dynamic transformation of the data and similarity across timescales by calculating the fractal dimension using allometric aggregation. From Wordnik.com. [BioMed Central - Latest articles] Reference
We assume that, for the formula Y ¼ aW b, the value of the power function where Y is the pharmacokinetic or physiological 'b' (or slope of the line from a log vs. log plot) is variable of interest, a is the allometric coef fi cient drug independent, unlike the intercept 'a', which is (and log a is the intercept of the line), W is the body drug dependent. From Wordnik.com. [Recently Uploaded Slideshows] Reference
Kim’s suggestion of reduced major axis regression will tell you about the allometric relationship of cranial capacity and mass. From Wordnik.com. [Fun with Hominin Cranial Capacity Datasets (and Excel) - The Panda's Thumb] Reference
2 Museum of Paleontology, University of California, Berkeley, California, United States of America Extended neoteny and late stage allometric growth increase morphological disparity between growth stages in at least some dinosaurs. From Wordnik.com. [PLoS ONE Alerts: New Articles] Reference
86 CH8 PHASE I: THE FIRST OPPORTUNITY FOR EXTRAPOLATION FROM ANIMAL DATA relationship between Fa and Caco-2 cell perme - One of the fi rst applications of allometric scaling ability, expressed as the apparent permeability was the use of the toxicity of anticancer agents in constant (Papp), as follows: animals to predict toxicity in humans children. From Wordnik.com. [Recently Uploaded Slideshows] Reference
Here, then, level of hepatic clearance, then in vitro-in vivo is a real-world example of, fi rst, how rat in vitro and scaling may be used to predict the fraction of in vivo preclinical data were used to develop and systemic clearance expected from this pathway. validate a scaling method for compound X in rat; If a compound undergoes a high level of renal and second, how the scaling method success - elimination, allometric scaling may be also used fully predicted in vivo overall drug clearance in to predict the clearance attributed to this pathway. humans. From Wordnik.com. [Recently Uploaded Slideshows] Reference
Similarly, allometric scaling feedback) leading to corrections and revisions. From Wordnik.com. [Recently Uploaded Slideshows] Reference
The elevations and slopes of each allometric equation have confidence intervals (CI. From Wordnik.com. [PLoS ONE Alerts: New Articles] Reference
Using this hepatic Cl using the rat-validated method, in con - well-stirred model, it has proved possible to predict junction with allometric scaling of renal Cl, the hepatic clearance from in vitro intrinsic clear - resulted in a fi ve-fold under-prediction of the ance rates in rat, dog and human (Table. From Wordnik.com. [Recently Uploaded Slideshows] Reference
· Curve fitting: Linear (Standard and Reduced Major Axis) with bootstrapping and permutation, lin-log (exponential), log-log (allometric), polynomial, logistic, von Bertalanffy, sum-of-sines, smoothing splines, LOESS smoothing, Gaussian (species packing), multiple regression. From Wordnik.com. [Softpedia - Windows - All] Reference
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