In MB, over-expression of c-MYC has been shown to cause anaplasia and correlate with unfavorable prognosis.    From Wordnik.com.  [BioMed Central - Latest articles] Reference

The processes such as inflammation, repair, hyperplasia, fibrosis, hypertrophy, dystrophy, degeneration, atrophy, necrosis, putrefaction, dysplasia, metaplasia, anaplasia, neoplasia etc. have to be appreciated as effects and hence not the cause of diseases in true sense.    From Wordnik.com.  [Recently Uploaded Slideshows] Reference