If the blastomere is aneuploid, this molecular tool, called "fluorescence in situ hybridization," or FISH, will unmask it.    From Wordnik.com.  [Delayed Childbearing] Reference

However, some leukemias and lymphomas are not aneuploid, and dysregulated expression of multiple genes is likely to be the main reason why aneuploidy is a marker for cells with abnormal phenotypes.    From Wordnik.com.  [Why deny only one part of science? IDists branch out into AIDS denial - The Panda's Thumb] Reference

In other words, more aneuploid embryos are formed than ever show up as pregnancies, and more pregnancies with aneuploid embryos spontaneously terminate at some early stage than ever continue to term.    From Wordnik.com.  [Delayed Childbearing] Reference

Feeding of freshly irradiated wheat resulted in significantly increased incidence of polyploid cells in bone marrow, aneuploid cells in testis, reduction in number of spermatogonia of types A, B and resting primary spermatocytes as well as a higher mutagenic index.    From Wordnik.com.  [Archive 2008-08-01] Reference

Two new gene sets associated with aneuploid eggs were identified.    From Wordnik.com.  [RxPG News : Latest Medical, Healthcare and Research News] Reference

However, most mosaic cleavage stage embryos are aneuploid in every cell.    From Wordnik.com.  [Recently Uploaded Slideshows] Reference

Six eggs in the study were found to be normal and six were identified as aneuploid.    From Wordnik.com.  [RxPG News : Latest Medical, Healthcare and Research News] Reference

The researchers used samples from 12 women with aneuploid pregnancies and six with normal pregnancies.    From Wordnik.com.  [Medlogs - Recent stories] Reference

DNA damage signal incurred by dysfunctional telomeres leads to tetraploid and, ultimately, aneuploid cells.    From Wordnik.com.  [WN.com - Articles related to Length of biological marker linked to cancer] Reference

Shi Q, King RW (2005) Chromosome nondisjunction yields tetraploid rather than aneuploid cells in human cell lines.    From Wordnik.com.  [PLoS ONE Alerts: New Articles] Reference

Shi Q, King R. W (2005) Chromosome nondisjunction yields tetraploid rather than aneuploid cells in human cell lines.    From Wordnik.com.  [PLoS Biology: New Articles] Reference

MYC traverse the G1 and S cell cycle phases and then arrest in the G2 phase becoming frequently aneuploid probably because of endoreduplication.    From Wordnik.com.  [PLoS ONE Alerts: New Articles] Reference

Under the new model, a series of hypotheses tests are formulated to explain the pattern of the genetic control of cancer through aneuploid loci.    From Wordnik.com.  [BioMed Central - Latest articles] Reference

These signals enabled the scientists to correctly identify the 12 women who carried aneuploid fetuses and the six whose pregnancies were normal.    From Wordnik.com.  [Scientific Frontline by SFL ORG Educational News Network] Reference

Cells lacking p53 became aneuploid after induced missegregation, indicating that the p53 pathway normally serves to limit the propagation of cells with odd numbers of chromosomes.    From Wordnik.com.  [Science Blog] Reference

Tumor cells tend to missegregate chromosomes at a particularly high frequency (a condition known as chromosomal instability, or CIN), which is probably why they are often aneuploid.    From Wordnik.com.  [Science Blog] Reference

Furthermore, these aneuploid cells develop an inherent genomic instability reminiscent of genuine cancer cells, perhaps because imbalanced gene expression also causes disruptions to mitosis.    From Wordnik.com.  [Science Blog] Reference

Posttranscriptional silencing of CENPA by RNA interference, resulting in CENP-A protein levels similar to those present in control cells, greatly reduced aneuploid cell numbers in pRb-depleted cells.    From Wordnik.com.  [BioMed Central - Latest articles] Reference

Aneuploidy exists in eggs and embryos of young women as well as older women, and it has been established that embryos containing both normal and aneuploid cells can correct themselves and result in normal live births.    From Wordnik.com.  [RxPG News : Latest Medical, Healthcare and Research News] Reference

There was a small but significant wrinkle to this story, however: normal, diploid cells stopped proliferating as soon as they gained or lost a chromosome, so they never converted into a cancer-like aneuploid cell line.    From Wordnik.com.  [Science Blog] Reference

Cancer Cells 'Chromosomes Hint at New Treatments birth defects or death, but the condition seems to benefit tumor cells, which are almost always aneuploid, noted Massachusetts Institute of Technology (MIT) researchers.    From Wordnik.com.  [Medlogs - Recent stories] Reference

Watch and listen as Titia de Lange and Teresa Davoli take you on a brief, personalized tour of their findings on how the persistent DNA damage signal incurred by dysfunctional telomeres leads to tetraploid and, ultimately, aneuploid cells.    From Wordnik.com.  [WN.com - Articles related to Length of biological marker linked to cancer] Reference

They analyzed the aneuploidy of four different mouse chromosomes and found that aneuploid cells all divided very slowly, grew too large, and displayed other metabolic changes that indicated that the cells were under stress and needed extra energy to cope with protein imbalances caused by aneuploidy.    From Wordnik.com.  [Medlogs - Recent stories] Reference

Per the publication of the company's clinical collaboration and testing, its proprietary Chromosomal Scanner technology was demonstrated a reliable and effective automated technological system to detect aneuploid cells in real-world specimens, that detection of aneuploid cells is diagnostic of cervical lesions and that the Chromosomal Scanner possesses superb performance at not only detecting cancer's chromosomal properties invites very effective, non-toxic therapeutic strategies.    From Wordnik.com.  [THE MEDICAL NEWS] Reference

100 90 80 Implantation rate 70 60 Aneuploidy rate 50 40 30 Cycles with all embryos aneuploid 20 10 0 30-34 35-38 39-42 43-50.    From Wordnik.com.  [Recently Uploaded Slideshows] Reference

After eliminating strains likely to be aneuploid in the deletion collection (.    From Wordnik.com.  [Naturejobs - All Jobs] Reference

In the teratocarcinoma line 2102Ep and in the teratocarcinoma-like line CH-ES1, the chromosomal complement was highly aneuploid (.    From Wordnik.com.  [PLoS ONE Alerts: New Articles] Reference

Although our results are not consistent with an earlier study that compared protein levels with gene dosage for 16 gene in aneuploid strains (.    From Wordnik.com.  [Naturejobs - All Jobs] Reference

"Although our older patients are at higher risk to produce aneuploid (chromosomally abnormal) embryos, once we identify euploid (chromosomally normal) blastocysts to transfer, these women have a similar clinical pregnancy rate as our CCS patients who are in their thirties.    From Wordnik.com.  [The Earth Times Online Newspaper] Reference

(2001) Dosage-dependent gene regulation in multicellular eukaryotes: implications for dosage compensation, aneuploid syndromes, and quantitative traits.    From Wordnik.com.  [PLoS ONE Alerts: New Articles] Reference

1) the efficacy of using an automated system to detect aneuploid cells in real-world specimens; 2) the detection of aneuploid cells is diagnostic of cervical lesions; and 3) the scanner's superb performance at not only detecting cancer but achieving the near theoretical maximum agreement with error containing data.    From Wordnik.com.  [THE MEDICAL NEWS] Reference