Another is its ability to increase blood cholesterol (by modifying enzyme activities) and to enhance atherogenesis, which is the early stage of cardiovascular disease.    From Wordnik.com.  [Kathy Freston: A Cure For Cancer? Eating A Plant-Based Diet] Reference

So these latest results suggest that the current thinking on atherogenesis is completely misguided, even among those who reject the significance of TC and LDL-C.    From Wordnik.com.  [Vytorin: Dis-Enhance-d | The Blog of Michael R. Eades, M.D.] Reference

“The effectiveness and rapidity of statin-induced decreases in coronary events led to the speculation that statins possess cholesterol-independent effects… we describe the numerous beneficial pleiotropic effects of statins that could modulate atherogenesis.”.    From Wordnik.com.  [Saturated fat debate | The Blog of Michael R. Eades, M.D.] Reference

~ A Unique Twin Study On The Increased Cardiometabolic Risk In Obesity -- "Study finds that obesity, already in its early stages and independent of genetic influences, is associated with deleterious alterations in the lipid metabolism known to facilitate atherogenesis, inflammation and insulin resistance.".    From Wordnik.com.  [Speedlinking 2/20/07] Reference

ICAM-1 did not seem to play a role in atherogenesis as early as LOX-1 and VCAM-1.    From Wordnik.com.  [PLoS ONE Alerts: New Articles] Reference

Steinberg D (1999) At last, direct evidence that lipoxygenases play a role in atherogenesis.    From Wordnik.com.  [PLoS ONE Alerts: New Articles] Reference

The potential involvement of extracellular histones in atherogenesis may be envisaged through several routes.    From Wordnik.com.  [PLoS ONE Alerts: New Articles] Reference

A large volume of basic and clinical evidence has strongly implicated chronic low-grade inflammation in atherogenesis.    From Wordnik.com.  [MedPageToday.com - medical news plus CME for physicians] Reference

(ICAM-1) in HIV-1 transgenic (HIV-1Tg) rats; these genes are all thought to play important roles in early atherogenesis.    From Wordnik.com.  [PLoS ONE Alerts: New Articles] Reference

Immune modulation of the inflammatory response has shown promise in animal models of atherogenesis and metabolic disease.    From Wordnik.com.  [BioMed Central - Latest articles] Reference

And some investigators have suggested that the chronic inflammation associated with the disease may actively promote atherogenesis.    From Wordnik.com.  [MedPageToday.com - medical news plus CME for physicians] Reference

However, it could be an interesting future area of investigation to study the impact of these proteins on atherogenesis in an animal model.    From Wordnik.com.  [PLoS ONE Alerts: New Articles] Reference

Conclusion: These findings demonstrate that rosiglitazone given for 6 weeks did not prevent atherogenesis at a vessel distant from the injury site.    From Wordnik.com.  [Business News and Business Products, Services, Reports and Advertising. Business News RSS Feed.] Reference

Although the HIV-infected rats did not display overt atherosclerosis, the up-regulation of LOX-1 and VCAM-1 indicates early atherogenesis in these rats.    From Wordnik.com.  [PLoS ONE Alerts: New Articles] Reference

Marx N, Duez H, Fruchart JC, Staels B (2004) Peroxisome proliferator-activated receptors and atherogenesis: regulators of gene expression in vascular cells.    From Wordnik.com.  [PLoS ONE Alerts: New Articles] Reference

The unexpected association of M2 reparative MØ with the initial stages of atherogenesis does not necessarily imply that this MØ phenotype contributes to the disease progression.    From Wordnik.com.  [PLoS ONE Alerts: New Articles] Reference

Activation of endothelial cells and subsequent increased expression of adhesion molecules by APOC3 may represent additional mechanisms by which the protein contributes to atherogenesis.    From Wordnik.com.  [PLoS ONE Alerts: New Articles] Reference

PROSPER is available on the Web site of the Vascular Biochemistry Department of the University of Glasgow Low-grade chronic inflammation is now widely thought to play an important role in the process of atherogenesis.    From Wordnik.com.  [PLoS Medicine: New Articles] Reference

The HIV-1Tg rat may be a promising model for further studies of the pathophysiology behind HIV-related cardiovascular disease, e.g. time-course of the atherogenesis and relative importance of HIV-infection and anti-retroviral treatment.    From Wordnik.com.  [PLoS ONE Alerts: New Articles] Reference

And, individuals with diabetes are especially susceptible to PAD because diabetes affects every vascular bed in the body and increases the risk for accelerated atherogenesis-the formation of plaque build up in the lining of the arteries-placing 18.2 million Americans at risk, he noted.    From Wordnik.com.  [Health News from Medical News Today] Reference

These are involved in regulating vasculogenesis and angiogenesis after ischemic injury, interactions of cells with adhesive proteins and blood vessels, proliferation of smooth muscle cells during atherogenesis, metabolism of lipoproteins and non-thrombogenic characteristics of endothelial cells.    From Wordnik.com.  [PLoS ONE Alerts: New Articles] Reference

Although to our knowledge no previous studies have investigated the role of HSPA8 in endothelium cells apoptosis, it might protect endothelium cells against apoptosis, which is believed to be the initiating event of atherogenesis and plays a crucial role in the transition from a stable endothelialized plaque to plaque erosion and thrombosis.    From Wordnik.com.  [PLoS ONE Alerts: New Articles] Reference

And I agree – today’s thinking is totally off the mark as it concerns atherogenesis.    From Wordnik.com.  [Vytorin: Dis-Enhance-d | The Blog of Michael R. Eades, M.D.] Reference

"By feeding HCD to zebrafish, we were able to reproduce many of the processes involved in early atherogenesis.    From Wordnik.com.  [innovations-report] Reference

"This finding may have implications for our understanding of atherogenesis (the process of plaque forming in arteries) in diabetes and for the design of more effective prevention strategies.    From Wordnik.com.  [Medlogs - Recent stories] Reference