The propargyl (alkyne) and azido groups are bioorthogonal reaction partners.    From Wordnik.com.  [PLoS ONE Alerts: New Articles] Reference

Extensive genetic screening allowed the team to target the azido probes efficiently.    From Wordnik.com.  [PhysOrg.com - latest science and technology news stories] Reference

The azido functionality was then reduced to amine on treatment with triphenyl phosphine and H.    From Wordnik.com.  [PLoS ONE Alerts: New Articles] Reference

Using propargyl - or azido-derivatives of the drug (so-called click chemistry derivatives) and a series of.    From Wordnik.com.  [PLoS ONE Alerts: New Articles] Reference

Because AZT has a N3 (azido) group on the ribose instead of a hydrogen, the next base cannot be added to the DNA chain and synthesis stops.    From Wordnik.com.  [Watching the Watchers] Reference

They then confirmed the presence of azido with fourier transform infrared (FTIR) difference spectroscopy, which measures stretching frequencies of the atoms in the amino acids that make up a protein.    From Wordnik.com.  [PhysOrg.com - latest science and technology news stories] Reference

Because azido has a unique vibration frequency that is sensitive to its surroundings, the team was able to use the spectroscopic data to confirm structural changes rhodopsin undergoes in light versus dark.    From Wordnik.com.  [PhysOrg.com - latest science and technology news stories] Reference

To apply their copper-free click chemistry to living mice, Bertozzi and her group delivered azides to the surfaces of target cells within the mice via a metabolic precursor, then labeled select glycans (those that bore corresponding azido sialic acids) by covalent reaction in vivo with a panel of cyclooctyne-FLAG peptide conjugates.    From Wordnik.com.  [THE MEDICAL NEWS] Reference

The three-nitrogen-atom azido is an especially good probe for three reasons: In contrast to other tags, azido does not exist naturally in mammals, which makes it easier to "see," or distinguish from other molecules in the cell; it is small enough to not interfere with a protein's normal functioning; and it has chemical properties that make it a good handle on which to hang other molecules, like fluorescent probes.    From Wordnik.com.  [PhysOrg.com - latest science and technology news stories] Reference