Hyperimmune responses, either at the initial immunisation challenge or in the amplification of immune response, can be observed in cellular mechanisms such as basophil degranulation, or at a molecular level, with changes in the levels of messengers such as leukotrienes; reduction of the intensity of these mechanisms are described in terms of molecular pharmacology, such as selective or nonselective inhibition of lipoxygenases.    From Wordnik.com.  [Citizendium, the Citizens' Compendium - Recent changes [en]] Reference

When an allergen binds between two IgE antibodies, it induces degranulation of a mast cell/basophil, which leads to the rapid release of histamine and the more gradual release of other mediators such as leukotrienes and cytokines.    From Wordnik.com.  [Archive 2006-03-01] Reference

Modulated basophil response is something that would affect asthma.    From Wordnik.com.  [Citizendium, the Citizens' Compendium - Recent changes [en]] Reference

"Human basophil degranulation triggered by very dilute antiserum against IgE".    From Wordnik.com.  [Citizendium, the Citizens' Compendium - Recent changes [en]] Reference

The basophil count is almost invariably increased, The eosinophils may also be increased.    From Wordnik.com.  [Recently Uploaded Slideshows] Reference

They are formed of a soft protoplasm, containing granules which are basophil in character.    From Wordnik.com.  [IV. Myology. 3. Tendons, Aponeuroses, and Fasciæ] Reference

Chronic myeloid leukaemia blast transformation: myeloid, with increased basophil precursors; peripheral blood.    From Wordnik.com.  [Recently Uploaded Slideshows] Reference

Most of the histamine released comes from mast cells in the damaged tissues and basophil granulocytes in the blood.    From Wordnik.com.  [Citizendium, the Citizens' Compendium - Recent changes [en]] Reference

Bunstead and colleagues detected measurable amounts of histamine, a mast cell and basophil mediator, in nasal polyp fluid.    From Wordnik.com.  [Yahoo! Answers: Latest Questions] Reference

In laboratory tests, we have shown that our Btk Inhibitor is a potent inhibitor of mast cell (and basophil) degranulation.    From Wordnik.com.  [THE MEDICAL NEWS] Reference

Featured articles include one on the basophil degranulation test, a test tube model of allergy, developed by Jean Sainte Laudy.    From Wordnik.com.  [Medlogs - Recent stories] Reference

Functionality of the recombinant allergens was assessed by enzymatic and biophysical analyses as well as basophil activation tests.    From Wordnik.com.  [BioMed Central - Latest articles] Reference

The vacuoles are filled with fluid, and the protoplasm between the spaces is clear, with occasionally a few scattered basophil granules.    From Wordnik.com.  [IV. Myology. 3. Tendons, Aponeuroses, and Fasciæ] Reference

From there, an integrative approach might say that this patient's basophil degradation is triggered too easily, with inflammation from histamine release.    From Wordnik.com.  [Citizendium, the Citizens' Compendium - Recent changes [en]] Reference

Belon P. "Application of flow cytometry to the analysis of the immunosuppressive effect of histamine dilutions on human basophil action: effect of cimetidine".    From Wordnik.com.  [Citizendium, the Citizens' Compendium - Recent changes [en]] Reference

Leucocytes having in their protoplasm granules which stain with basic dyes (basophil) have been described as occurring in human blood, but they are rarely found except in disease.    From Wordnik.com.  [V. Angiology. 2. The Blood] Reference

Inc. White blood cell Leukocytes include granulocytes, monocytes, and lymphocytes. eosinophil granulocytes basophil neutrophil Mosby items and derived items © 2005, 2001 by Mosby.    From Wordnik.com.  [Recently Uploaded Slideshows] Reference

These marrow cells proper, or myelocytes, resemble in appearance lymphoid corpuscles, and like them are ameboid; they generally have a hyaline protoplasm, though some show granules either oxyphil or basophil in reaction.    From Wordnik.com.  [II. Osteology. 2. Bone] Reference

Neutrophil eosinophil basophil lymphocyte monocyte Mosby items and derived items © 2005.    From Wordnik.com.  [Recently Uploaded Slideshows] Reference

Histamine dilutions modulate basophil activity.    From Wordnik.com.  [Citizendium, the Citizens' Compendium - Recent changes [en]] Reference

1993) Human basophil degranulation is not triggered by very dilute antiserum against human IgE ".    From Wordnik.com.  [Citizendium, the Citizens' Compendium - Recent changes [en]] Reference

0.05) for monocyte, eosinophil, and basophil counts, percentage G1+ neutrophils, or percentage oxidative burst positive neutrophils.    From Wordnik.com.  [BioMed Central - Latest articles] Reference