Manufacturers of various forms of beta-interferon include Biogen Idec Inc. From Wordnik.com. [New Insight Into Multiple-Sclerosis Treatment] Reference
One pathway corresponded to people who respond to beta-interferon, the other to people who don't. From Wordnik.com. [New Insight Into Multiple-Sclerosis Treatment] Reference
One pathway corresponded to people who responded to beta-interferon, the other to people who didn't. From Wordnik.com. [Multiple-Sclerosis Study Could Help Patients] Reference
But beta-interferon carries flu-like side effects and Tysabri has led to fatal brain disease in rare instances. From Wordnik.com. [MS Program Halted Amid Controversy] Reference
Among the MS patients who do respond to beta-interferon, the effectiveness of the drug may potentially be greater than now believed. From Wordnik.com. [Multiple-Sclerosis Study Could Help Patients] Reference
Differentiating between responders and nonresponders to beta-interferon could help thousands of people skip the drug and avoid the flu-like symptoms that accompany it, while assuring others that they are likely to benefit, doctors said. From Wordnik.com. [New Insight Into Multiple-Sclerosis Treatment] Reference
The researchers, led by Lawrence Steinman and Robert C. Axtell of Stanford's neurology department, concluded that a simple blood test could indicate which patients were most likely to benefit from beta-interferon, which minimizes the relapses suffered by some MS patients. From Wordnik.com. [Multiple-Sclerosis Study Could Help Patients] Reference
The researchers, led by Lawrence Steinman and Robert C. Axtell of Stanford's neurology department, concluded that a simple blood test could indicate which patients are most likely to benefit from beta-interferon, which minimizes the relapses suffered by some but not all MS patients. From Wordnik.com. [New Insight Into Multiple-Sclerosis Treatment] Reference
In contrast, people given beta-interferon showed signs of progressively worsening disability. From Wordnik.com. [Radio New Zealand News Headlines] Reference
In fact, said Steinman, there is some evidence that beta-interferon actually worsened these patients 'conditions. From Wordnik.com. [THE MEDICAL NEWS] Reference
Without knowing which samples came from patients who had responded well or poorly to beta-interferon treatment, they went about measuring IL-17 levels in those samples. From Wordnik.com. [THE MEDICAL NEWS] Reference
"The other side of the coin is that beta-interferon, if it's given only to those who are predisposed to respond to it, could turn out to be a far better drug than we ever imagined.". From Wordnik.com. [THE MEDICAL NEWS] Reference
This was confirmed by brain scans in which alemtuzumab patients showed signs that their brains had actually increased in size, while the beta-interferon patients 'brains shrank over time. From Wordnik.com. [British Blogs] Reference
Those with very low detectable blood levels of IL-17F responded well to beta-interferon treatment, experiencing no relapses or instances of required steroids (to quickly shut down a malfunctioning immune system). From Wordnik.com. [THE MEDICAL NEWS] Reference
A few years ago while still a PhD student at the University of Alabama, the study's first author, Robert Axtell, had shown that, as in people with multiple sclerosis, beta-interferon can reverse paralysis in mice with EAE. From Wordnik.com. [THE MEDICAL NEWS] Reference
The researchers found that beta-interferon improved the condition of animals whose EAE had been induced by gamma-interferon-secreting T cells, but exacerbated symptoms in those whose EAE had been induced by IL-17-secreting T cells. From Wordnik.com. [THE MEDICAL NEWS] Reference
Another postdoctoral scholar in the Steinman lab, Brigit deJong, MD, the study's second author, had previously been involved in research in Amsterdam in which multiple-sclerosis patients were treated with beta-interferon and meticulously followed up. From Wordnik.com. [THE MEDICAL NEWS] Reference
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