Bile canalicular morphometry in arteriohepatic dysplasia.    From Wordnik.com.  [Alagille Syndrome Related Reading] Reference

We show that canalicular membranes of cholestatic Atp8b1-deficient mice have.    From Wordnik.com.  [Journal of Biological Chemistry current issue] Reference

Experimental determination of the permeability in the lacunar-canalicular porosity of bone.    From Wordnik.com.  [SpaceRef Top Stories] Reference

An alternative hypothesis arose in 2007, when Weinbaum and his colleagues identified integrin attachments on the canalicular wall.    From Wordnik.com.  [News from The Scientist] Reference

Atp8b1-deficient mice display a dramatic increase in the biliary extraction of cholesterol from the canalicular (apical) membrane of the hepatocyte.    From Wordnik.com.  [Journal of Biological Chemistry current issue] Reference

Burwinkel B, Schirmacher P, Knisely AS, Zschocke J, Sauer P.: A mutation in the canalicular phospholipid transporter gene, ABCB4, is associated with cholestasis, ductopenia, and cirrhosis in adults.    From Wordnik.com.  [EurekAlert! - Breaking News] Reference

Here we studied the hypothesis that disproportionate cholesterol extraction from the canalicular membrane impairs the activity of the bile salt transporter, ABCB11, and as a consequence causes cholestasis.    From Wordnik.com.  [Journal of Biological Chemistry current issue] Reference

As interstitial fluid flows through the networks of cavities and canals known as the lacuno-canalicular network, it pulls on "tethering" filaments that link osteocytes, or bone cells, and the walls of the canaliculi.    From Wordnik.com.  [News from The Scientist] Reference

Our data demonstrate that membrane cholesterol content is a critical determinant of ABCB11 / ABCC2 transport activity, provide an explanation for the etiology of ATP8B1 disease, and suggest a novel mechanism protecting the canalicular membrane.    From Wordnik.com.  [Journal of Biological Chemistry current issue] Reference

Originally proposed as a system for delivering nutrients and removing waste products from bone cells called osteocytes, scientists now recognize fluid flow through this lacuno-canalicular network as providing bone tissue with important mechanical loading information.    From Wordnik.com.  [News from The Scientist] Reference

In 2001, Weinbaum and his colleagues suggested that "tethering" filaments strung between bone cells and the walls of the lacuno-canalicular network may act as a sensor-and amplifier-of physical forces. 10 Indeed, the drag forces inflicted on these tethers as the result of fluid flow can amplify a mechanical signal 10 to 100 times greater than a signal imposed directly on the bone matrix, but how this signal elicits a biochemical response is unclear.    From Wordnik.com.  [News from The Scientist] Reference

11 Bile canalicular transporters.    From Wordnik.com.  [THE MEDICAL NEWS] Reference