The publications advocate use of the assay to identify a need for cobalamin/folate supplements. From Wordnik.com. [Supreme Court Patent Decision -- Can Thinking Infringe a Patent?] Reference
A method for detecting a deficiency of cobalamin or folate in warm-blooded animals comprising the steps of. From Wordnik.com. [Archive 2005-10-01] Reference
These publications state that elevated total homocysteine correlates to cobalamin/folate deficiency and that this deficiency can be treated with vitamin supplements. From Wordnik.com. [Supreme Court Patent Decision -- Can Thinking Infringe a Patent?] Reference
In terms of this structure, one can begin to understand some of the uses to which the cobalamin nucleus is put in nature, for example, its part in the transfer of methyl groups. From Wordnik.com. [Nobel Lecture The X-Ray Analysis Of Complicated Molecules] Reference
Again the intensities of the X-ray diffraction spectra were measured, Patterson and electron-density distributions were calculated, atoms belonging to the best known parts of the cobalamin molecule being placed first in the calculations. From Wordnik.com. [Nobel Lecture The X-Ray Analysis Of Complicated Molecules] Reference
There followed directly an explanation of the observed great instability of the molecule to light and cyanide ions -- instability which had led to the failure of earlier investigations to recognise its existence and to isolate, in its place, cyano-cobalamin. From Wordnik.com. [Nobel Lecture The X-Ray Analysis Of Complicated Molecules] Reference
The following chart shows the World's Healthiest Foods that are either an excellent, very good, or good source of vitamin B12 (cobalamin). From Wordnik.com. [The World's Healthiest Foods] Reference
Delpre G, Stark P, and Niv Y. Sublingual therapy for cobalamin deficiency as an alternative to oral and parenteral cobalamin supplementation. From Wordnik.com. [The World's Healthiest Foods] Reference
Serum cobalamin levels were ten fold higher in individuals than those taking the current commercial B12 formulation and a greater than 90\% reduction in absorption time was seen. From Wordnik.com. [News] Reference
I speak as a former vegetarian whose life was destroyed by supplementing with the wrong cobalamin, the inactive cyanocobalamin which is very stable and very ineffective in many peolple. From Wordnik.com. [Original Signal - Transmitting Buzz] Reference
Since the cobalamin forms of the vitamin are the only ones known with certainty to play an active role in the body, alternative forms of B12 like cobamamide may be less preferable for supplementation. From Wordnik.com. [The World's Healthiest Foods] Reference
(cobalamin, or vitamin B12) had finally been isolated in 1948, it became clear that even healthy people needed this factor but that they absorbed it efficiently so that a normal mixed diet was sufficient. From Wordnik.com. [The Nobel Prize and the Discovery of Vitamins] Reference
In addition, the Company is developing earlier stage compounds in its pipeline and has an oral cobalamin nanopolymer drug delivery technology, which has demonstrated positive results for the delivery of insulin by mouth in preclinical animal models. From Wordnik.com. [SeekingAlpha.com: Home Page] Reference
A method for detecting a deficiency of cobalamin or folate in warm-blooded animals comprising the steps of: assaying a body fluid for an elevated level of total homocysteine; and correlating an elevated level of total homocysteine in said body fluid with a deficiency of cobalamin or folate. From Wordnik.com. [Patent Law Blog (Patently-O)] Reference
This seminal discovery was the subject of an article entitled "The protein and the gene encoding the receptor for the cellular uptake of transcobalamin - bound cobalamin" and which was published in the scientific journal "Blood" in January 2009, by Dr. Edward Quadros and his colleagues at SUNY. From Wordnik.com. [FinanzNachrichten.de: Aktuelle Nachrichten] Reference
Corp. dissent is its failure to recognize the difference between a patent ineligible relationship - i.e., that between high homocysteine levels and folate and cobalamin deficiencies - and a patent eligible process for applying that relationship to achieve a useful, tangible, and concrete result - i.e., diagnosis of potentially fatal conditions in patients. From Wordnik.com. [Groklaw] Reference
LabCorp’s articles thus promote total homocysteine assays for detecting cobalamin/folate deficiency. From Wordnik.com. [Supreme Court Patent Decision -- Can Thinking Infringe a Patent?] Reference
Accordingly, a reasonable jury could find intent to induce infringement because LabCorp’s articles state that elevated total homocysteine correlates to cobalamin/folate deficiency. From Wordnik.com. [Supreme Court Patent Decision -- Can Thinking Infringe a Patent?] Reference
Assaying a body fluid for an elevated level of total homocysteine; and correlating an elevated level of total homocysteine in said body fluid with a deficiency of cobalamin or folate. From Wordnik.com. [Archive 2005-10-01] Reference
(cobalamin) contained in one serving size of the food, the percent Daily Value (DV\%) that this amount represents, the nutrient density that we calculated for this food and nutrient, and the rating we established in our rating system. From Wordnik.com. [The World's Healthiest Foods] Reference
In the laboratory, methylcobalamin can be made by a series of reactions involving the reduction of aquocobalamin to a compound, probably cobalamin hydride, which easily exchanges with methyl compounds such as diazomethane or methyl sulphate; in nature, reduction also seems necessary for methyl transfer; the experiments of D.D. Woods and his colleagues strongly suggest that methylcobalamin is the actual intermediate in one of the pathways by which methyl groups are transferred from methyltetrahydrofolate to homocysteine to form methionine 20. From Wordnik.com. [Nobel Lecture The X-Ray Analysis Of Complicated Molecules] Reference
Determinants of arsenic metabolism: blood arsenic metabolites, plasma folate, cobalamin, and homocysteine concentrations in maternal-newborn pairs. (. From Wordnik.com. [West Seattle Blog...] Reference
Accurate and early diagnosis of cobalamin deficiency is especially important because it can also lead to incapacitating and life-threatening neuropsychiatric abnormalities. "). From Wordnik.com. [Groklaw] Reference
1928, the stomachs of pernicious anemia patients were abnormal in failing to secrete an "intrinsic factor" that combined with cobalamin and greatly increased the subsequent efficiency of its absorption from the small intestine. From Wordnik.com. [The Nobel Prize and the Discovery of Vitamins] Reference
Simple, vitamin B12 or cobalamin. From Wordnik.com. [Business and financial news - CNNMoney.com] Reference
Nutrient vitamin B12 (cobalamin) 2.45 mcg. From Wordnik.com. [The World's Healthiest Foods] Reference
32-40 ( "Accurate and early diagnosis of cobalamin and folate deficiencies ... is important because these deficiencies can lead to life-threatening hematologic abnormalities. From Wordnik.com. [Groklaw] Reference
(B-9) and cobalamin (B-12). From Wordnik.com. [Livescience.com] Reference
Names for B12 include: cobrynamide, cobinamide, cobamide, cobalamin, hydroxcobalamin, aquocobalamin, nitrotocobalamin, and cyanocobalamin. From Wordnik.com. [The World's Healthiest Foods] Reference
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