Dr. Brody and colleagues found that in pancreatic cancer, HuR helps to regulate an enzyme called deoxycytidine kinase (dCK), which is responsible for metabolizing and activating gemcitabine. From Wordnik.com. [Emaxhealth] Reference
Reichard repeated and extended this experiment with U-14C uridine in 1957 with much the same result for the deoxycytidine and thymidine4. From Wordnik.com. [Irwin Rose - Autobiography] Reference
It was obvious for me to ask if there might be direct utilization of the whole of cytidine, ribose and all, in the biosynthesis of deoxycytidine. From Wordnik.com. [Irwin Rose - Autobiography] Reference
These in vitro techniques employ treatment of cultured cells with 5-aza-deoxycytidine. From Wordnik.com. [PLoS ONE Alerts: New Articles] Reference
Cells were treated with 5 µM 5-Aza-deoxycytidine for 5 days and 300 nM TSA for last 24 hours. From Wordnik.com. [PLoS ONE Alerts: New Articles] Reference
Mice without the deoxycytidine kinase (dCK) enzyme have defects in their adaptive immune system, pro. From Wordnik.com. [THE MEDICAL NEWS] Reference
Posted on: Tuesday, 22 December 2009, 14: 19 CST Mice without the deoxycytidine kinase (dCK) enzyme have defects in their adaptive immune system, producing very low levels of both T. From Wordnik.com. [WN.com - Articles related to The link between poor sleep and diabetes] Reference
Since 5-Aza-2-deoxycytidine-induced hypomethylation resulted in several phenotypic changes in the SRC cells in vitro, we wanted to determine if the treatment would affect cell growth in vivo. From Wordnik.com. [PLoS ONE Alerts: New Articles] Reference
Mice without the deoxycytidine kinase (dCK) enzyme have defects in their adaptive immune system, producing very low levels of both T and B lymphocytes, the major players involved in immune response, according to a study by researchers with UCLA's Jonsson Comprehensive. From Wordnik.com. [THE MEDICAL NEWS] Reference
Mice without the deoxycytidine kinase (dCK) enzyme have defects in their adaptive immune system, producing very low levels of both T and B lymphocytes, the major players involved in immune response, according to a study by researchers with UCLA's Jonsson Comprehensive Cancer Center. From Wordnik.com. [PhysOrg.com - latest science and technology news stories] Reference
(a) Initially, minimally-transformed cell lines were treated with 5-aza-deoxycytidine and TSA to unmask epigenetically silenced genes. From Wordnik.com. [PLoS ONE Alerts: New Articles] Reference
Results are shown for 7 animals with tumors induced from untreated cells (SRC control) and for 7 animals with tumors induced from 5-Aza-2-deoxycytidine-treated cells (SRC. From Wordnik.com. [PLoS ONE Alerts: New Articles] Reference
5-aza-deoxycytidine treatment or genetic deletion of DNA methyltransferases. From Wordnik.com. [Naturejobs - All Jobs] Reference
5-Aza-2-deoxycytidine-induced changes in gene expression had a significant impact on the phenotype of the SRC cells as tumors derived from 5-Aza-2-deoxycytidine treated cells produced larger tumors than tumors derived from untreated cells (. From Wordnik.com. [PLoS ONE Alerts: New Articles] Reference
5-Aza-2-deoxycytidine-treated SRC cells. From Wordnik.com. [PLoS ONE Alerts: New Articles] Reference
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