That a minor hiccup could occur during brain development in the womb, perhaps caused by a hormonal glitch, or environmental factors such as administration of diethylstilboestrol during pregnancy seems very plausible.    From Wordnik.com.  [Brains, Gender, Humour, Pain, and possibly Depression] Reference

She believes there are parallels with another man-made hormone, diethylstilboestrol (DES), which was used to prevent miscarriage in the 1950s.    From Wordnik.com.  [Home | Mail Online] Reference