ATT is produced by the liver and its job it to prevent an enzyme found in the lungs, called elastase, which breaks down the elastic fibers, called elastin, that make up the airways and the alveolar walls.    From Wordnik.com.  [CreationWiki - Recent changes [en]] Reference

Determination of elastase activity, rhamnolipid and signal molecule production.    From Wordnik.com.  [PLoS ONE Alerts: New Articles] Reference

MMP-12 (macrophage elastase) is a protease known to be involved in the progression of lung disease.    From Wordnik.com.  [BioMed Central - Latest articles] Reference

However, ultimately we would need to measure the concentration of elastase that schistosoma releases.    From Wordnik.com.  [OpenWetWare - Recent changes [en]] Reference

In healthy individuals, neutrophils never release destructive human neutrophil elastase into nearby tissue.    From Wordnik.com.  [Digital50.com Digital 50 Daily Industry News RSS Feed] Reference

It is also attempted to determine how long it will take for the protease or elastase to cleave enough peptides.    From Wordnik.com.  [OpenWetWare - Recent changes [en]] Reference

The reduction of ATT in such an individual allows the destruction of tissue in the lungs by elastase to occur unopposed.    From Wordnik.com.  [CreationWiki - Recent changes [en]] Reference

Cryz SJ, Iglewski BH (1980) Isolation and characterization of Pseudomonas aeruginosa PAO mutant that produces altered elastase.    From Wordnik.com.  [PLoS ONE Alerts: New Articles] Reference

The temperature of local joints affects levels of destructive enzymes such as collagenase, elastase, hyaluronidase, and protease.    From Wordnik.com.  [Recently Uploaded Slideshows] Reference

Isolates were characterized with regard to QS signal molecules, alginate, rhamnolipid and elastase production and mutant frequency.    From Wordnik.com.  [PLoS ONE Alerts: New Articles] Reference

The aim of this model is to determine the concentration of Schistosoma elastase or TEV protease that should be added to the bacteria to trigger the response.    From Wordnik.com.  [OpenWetWare - Recent changes [en]] Reference

The most common cause of inherited SCN is a heterozygous mutation (where one copy of the gene is mutated and the other is not) in the neutrophil elastase (ELA2) gene.    From Wordnik.com.  [National Institutes of Health (NIH) News Releases] Reference

SLPI is an inhibitor of neutrophil elastase and its dramatic upregulation thus indicates that control of elastase activity is an important feature of the uterine infection.    From Wordnik.com.  [PLoS ONE Alerts: New Articles] Reference

PRT-201 is a recombinant human elastase that is being studied for its ability to improve arteriovenous fistula (AVF) surgery outcomes in patients requiring chronic hemodialysis.    From Wordnik.com. Reference

The dynamics of the functionality of QS systems in the clinical strains were correlated to rhamnolipids and elastase production as well as to the mutational frequencies of the isolates.    From Wordnik.com.  [PLoS ONE Alerts: New Articles] Reference

The supernatant was either dialyzed against sterile water (for elastase activity) or sterile filtered using 0.2 µm pore filters (16543; Sartorius), frozen and kept for further analysis.    From Wordnik.com.  [PLoS ONE Alerts: New Articles] Reference

The concomitant development of QS malfunction significantly correlated with the reduced production of rhamnolipids and elastase and with the occurrence of mutations in the regulatory genes lasR and rhlR.    From Wordnik.com.  [PLoS ONE Alerts: New Articles] Reference

Proteins bound to the columns were eluted with glycine (pH 2.7), digested with a set of proteases (varying combinations of trypsin, subtilisin, elastase, and endopeptidase Lys-C) to achieve higher sequence coverage, and analyzed by MS.    From Wordnik.com.  [PLoS Biology: New Articles] Reference

From each plate (representing an isolate) one colony was selected and grown as a overnight culture in either ox-broth (for elastase activity) or AB trace minimal medium containing 3 mM glucose (32) at 37°C with shaking (rhamnolipid and signal molecules production).    From Wordnik.com.  [PLoS ONE Alerts: New Articles] Reference

"The progression of emphysema in mice exposed to elastase was significantly improved by the gene therapy as evidenced by improvements in lung compliance and alveolar size," said Andrew Wilson, MD, lead author of the study and an assistant professor of medicine at BUSM.    From Wordnik.com.  [PhysOrg.com - latest science and technology news stories] Reference

His team now suspects the inappropriate activation of the "happiness signal" - the molecular target of rapamycin, or mTOR, cell signaling pathway-may trigger neutrophils to release large quantities of human neutrophil elastase, the enzyme that destroys the elastic fiber of lung tissue.    From Wordnik.com.  [Digital50.com Digital 50 Daily Industry News RSS Feed] Reference

Neutrophils from healthy volunteers were incubated with DFP (2.5 mM), and neutrophil elastase (NE) activity; hypodiploid DNA formation; caspases-3 and -8 processing and activity; exteriorization of phosphatidylserine (PS); oxidative burst activity and hydrogen peroxide release were measured.    From Wordnik.com.  [BioMed Central - Latest articles] Reference

(see table) .1 There are also autosomal dominant and sporadic forms of severe congenital neutropenia that are caused by mutations in the ELA2 gene, which encodes the serine protease neutrophil elastase. 2 ELA2 mutations account for approximately 50 to 60\% of cases of the disorder.    From Wordnik.com.  [Medlogs - Recent stories] Reference

3-oxo-C12-HSL or none of the QS molecules and distribution of the rhamnolipid and elastase levels in CF.    From Wordnik.com.  [PLoS ONE Alerts: New Articles] Reference

(1984) Interaction of Pseudomonas aeruginosa alkaline protease and elastase with human polymorphonuclear leukocytes in vitro.    From Wordnik.com.  [PLoS ONE Alerts: New Articles] Reference