"Now we know what cells ethosuximide targets in C. elegans," Kornfeld says.    From Wordnik.com.  [Medlogs - Recent stories] Reference

The anticonvulsant ethosuximide disrupts sensory function to extend C. elegans lifespan.    From Wordnik.com.  [Medlogs - Recent stories] Reference

They also determined ethosuximide was associated with significantly fewer negative effects on attention.    From Wordnik.com.  [ Analysis] Reference

This suggests that ethosuximide extends lifespan by inhibiting the function of specific chemosensory neurons.    From Wordnik.com.  [JAMA current issue] Reference

These mutations inhibit the activity of some sensory neurons in the worm, and that helped the researchers conclude that ethosuximide also directly affected these neurons.    From Wordnik.com.  [Medlogs - Recent stories] Reference

In the long term, Kornfeld's goal is to identify compounds that could potentially delay human aging Roundworms treated with ethosuximide lived up to 29 percent longer than normal.    From Wordnik.com.  [Clipmarks | Live Clips] Reference

March 13th, 2010 more imagesLONDON - One of the oldest available anti-seizure medications, ethosuximide, is the most effective treatment for childhood absence epilepsy, a new study says.    From Wordnik.com.  [Gaea Times (by Simple Thoughts) Breaking News and incisive views 24/7] Reference

Now, further investigating the effect of one of those compounds, ethosuximide, the researchers found that it had the same life-extending effect as some well-studied genetic mutations in C. elegans.    From Wordnik.com.  [Medlogs - Recent stories] Reference

March 13th, 2010 LONDON - Doctors at OHSU Doernbecher Children's Hospital have claimed that ethosuximide, one of the oldest available anti-seizure medications, is the most effective treatment for childhood absence epilepsy.    From Wordnik.com.  [Gaea Times (by Simple Thoughts) Breaking News and incisive views 24/7] Reference

"Like roundworms that are grown in a food-scarce environment, the worms exposed to the anticonvulsant ethosuximide lived longer.    From Wordnik.com.  [Medlogs - Recent stories] Reference

Zarontin (ethosuximide).    From Wordnik.com.  [Brain Blogger] Reference