West DC, Shaw DM, Lorenz P, Adzick NS, Longaker MT: Fibrotic healing of adult and late gestation fetal wounds correlates with increased hyaluronidase activity and removal of hyaluronan. From Wordnik.com. [CHOP scarless fetal wound healing publications] Reference
Agglutinability Pasteurella multocida cure hyaluronidase. From Wordnik.com. [xml's Blinklist.com] Reference
Halozyme's recombinant hyaluronidase received FDA approval in 2005. From Wordnik.com. [Fore, right!] Reference
Hi, just a quick question on the pegylated hyaluronidase the Phase I study. From Wordnik.com. [SeekingAlpha.com: Home Page] Reference
Cumulus cells were removed using 0. 3\% hyaluronidase for 1-3 min in the same solution. From Wordnik.com. [PLoS ONE Alerts: New Articles] Reference
The donor CU cells were collected from ovulated MII oocytes by treatment with hyaluronidase. From Wordnik.com. [PLoS ONE Alerts: New Articles] Reference
HyQ is a immunoglobulin therapy facilitated subcutaneously by recombinant human hyaluronidase. From Wordnik.com. [Baxter International CEO Discusses Q3 2010 Earnings Call Transcript -- Seeking Alpha] Reference
Ventricular cardiac myocytes were isolated via collagenase-hyaluronidase digestion as previously described. From Wordnik.com. [PLoS ONE Alerts: New Articles] Reference
Now the company is conducting an early-stage study of hyaluronidase in patients with various solid tumor types. From Wordnik.com. [Fore, right!] Reference
In animal studies, Halozyme has used hyaluronidase to break down the protective gel coating, causing the tumor to collapse. From Wordnik.com. [Fore, right!] Reference
Frost became interested in hyaluronidase as a young researcher at UC San Francisco, where he earned a doctorate in pathology. From Wordnik.com. [Fore, right!] Reference
Enhanze ™ technology (rHuPH20, recombinant human hyaluronidase) in a subcutaneous formulation with Roche's anticancer biologic. From Wordnik.com. Reference
The temperature of local joints affects levels of destructive enzymes such as collagenase, elastase, hyaluronidase, and protease. From Wordnik.com. [Recently Uploaded Slideshows] Reference
The tissue was then digested with collagenase, hyaluronidase, DNase in Iscoves Modified Dulbeccos Medium (IMDM) for 90 minutes at 37°. From Wordnik.com. [PLoS ONE Alerts: New Articles] Reference
Based on this observation, we believe that our pegylated hyaluronidase enzyme may eventually play an important role in solid tumor treatment. From Wordnik.com. [SeekingAlpha.com: Home Page] Reference
The pegylated version of our hyaluronidase enzyme began its first Phase I clinical study earlier this year and is still in early stage development. From Wordnik.com. [SeekingAlpha.com: Home Page] Reference
The preclinical data support furthering Baxter's Phase III development program evaluating recombinant human hyaluronidase to deliver immune globulins. From Wordnik.com. Reference
Baxter is researching investigational 10 percent immune globulin therapy, which is GAMMAGARD LIQUID administered with recombinant human hyaluronidase. From Wordnik.com. Reference
N-acetylglucosamine; HAase, hyaluronidase; MALDI-TOF-MS, matrix-assisted laser desorption ionization-time of flight mass spectrometry; MMP, matrix metalloprotease. From Wordnik.com. [Naturejobs - All Jobs] Reference
First some background: Halozyme's enzyme is a genetically-engineered copy of human hyaluronidase, which breaks down a gel-like substance found in cartilage and skin. From Wordnik.com. [Fore, right!] Reference
For more information about Baxter's studies of immune globulin therapy with recombinant human hyaluronidase for patients with PID, listen to Baxter's podcast by visiting. From Wordnik.com. Reference
Hylenex (hyaluronidase human injection) in early October at the scientific assembly of the American College of Emergency Physicians (ACEP) for use in pediatric rehydration. From Wordnik.com. Reference
The company believed there was room for recombinant hyaluronidase, which would lack the foreign proteins and other impurities inherent in enzymes derived from slaughterhouse animals. From Wordnik.com. [Fore, right!] Reference
The experimental injection is aided by the enzyme hyaluronidase, a genetically-altered spreading agent that helps increase the body's ability to transmit lost fluids back into its system. From Wordnik.com. [Baylor College of Medicine News] Reference
Completing patient enrollment in Baxter's pivotal Phase III study of GAMMAGARD LIQUID with rHuPH20 (PH20) hyaluronidase enzyme for the treatment of primary immunodeficiency disorder (PID). From Wordnik.com. [Digital50.com Digital 50 Daily Industry News RSS Feed] Reference
(IGIV), marketed as KIOVIG in the European Union, with Halozyme's recombinant human hyaluronidase enzyme (rHuPH20, Enhanze (TM) Technology) for the treatment of primary immunodeficiency (PID). From Wordnik.com. [Health News from Medical News Today] Reference
The bioavailability of antibodies in the 20 percent immune globulin therapy delivered with recombinant human hyaluronidase was comparable with immune globulin 10 percent delivered intravenously. From Wordnik.com. Reference
Some strains may not always test positive because they may be encapsulated. lipases, hyaluronidase and protein receptors are all extracellular enzymes that play an important role in pathogenesis. From Wordnik.com. [Citizendium, the Citizens' Compendium - Recent changes [en]] Reference
Baxter presented positive results from its Gammagard enhanced technology Phase I / II clinical trial that tested subcutaneous delivery of Gammagard following administration of our proprietary hyaluronidase enzyme. From Wordnik.com. [Biotech Sector and Stocks Analysis from Seeking Alpha] Reference
Furthermore, comparison of subcutaneously administered 20 percent immune globulin, with and without recombinant human hyaluronidase, showed improved bioavailability with the addition of recombinant human hyaluronidase. From Wordnik.com. Reference
These three agreements are expected to cover the commercial production of recombinant human hyaluronidase (rHuPH20) to be used in the manufacture of both current products as well as certain partnered product candidates such as subcutaneous. From Wordnik.com. [The Earth Times Online Newspaper] Reference
"Entering Phase III clinical development is an important achievement for our hyaluronidase enzyme and for our collaboration with Baxter. From Wordnik.com. [Health News from Medical News Today] Reference
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