On the presence of collagen in the brain of calf and man with special reference to the isolation of an unknown protein containing hydroxyproline by Leonard Wartofsky. From Wordnik.com. [Solitary Confinement In U.S. Prisons Making Thousands Psychotic] Reference
These animal express collagen, but it doesn't contain hydroxyproline. From Wordnik.com. [ScienceBlogs Channel : Life Science] Reference
Almost one third of the amino acids are glycine and one quarter is proline or hydroxyproline. From Wordnik.com. [NutraIngredients-USA RSS] Reference
• X-ray diffraction studies reveal a cylinder of water surrounding the triple-helix which is hydrogen-bonded to the hydroxyproline side-chains. From Wordnik.com. [Recently Uploaded Slideshows] Reference
The total collagen content of the left lung was determined by measuring hydroxyproline content in aliquots of pulverized left lung as described previously. From Wordnik.com. [PLoS ONE Alerts: New Articles] Reference
In contrast, HPLC determination of hydroxyproline content, as a surrogate marker for collagen protein levels, demonstrated no significant differences between the bleomycin groups - in agreement with the Ashcroft scores. From Wordnik.com. [PLoS ONE Alerts: New Articles] Reference
As a clarification of the above, molecular oxygen, as I understand it, is necessary for the post-transcriptional hydroxylation of proline to hydroxyproline - ie the oxygen in the hydroxyproline does not come from water, but is added from an O2 molecule by an oxygenase enzyme. From Wordnik.com. [ScienceBlogs Channel : Life Science] Reference
+MSCs-KGF-eGFP groups while H) there was no difference in lung collagen accumulation as measured by reverse-phase HPLC quantification of lung hydroxyproline. From Wordnik.com. [PLoS ONE Alerts: New Articles] Reference
HPLC quantification of hydroxyproline content demonstrated a significant increase in total lung collagen in mice given bleomycin alone compared with saline-treated animals (p = 0.0179. From Wordnik.com. [PLoS ONE Alerts: New Articles] Reference
Adzick NS, Harrison MR, Glick PL, Beckstead JH, Villa RL, Scheuenstuhl H, Goodson WH III: Comparison of fetal, newborn, and adult rabbit wound healing by histologic, enzyme-histochemical, and hydroxyproline determinations. From Wordnik.com. [CHOP scarless fetal wound healing publications] Reference
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